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Arroyo Seco may refer to:

Places

Mexico

• Arroyo Seco Municipality
• Arroyo Seco, Querétaro

United States

• Arroyo Seco, New Mexico, an unincorporated community in Taos County, New Mexico
• El Valle de Arroyo Seco, New Mexico, a census designated place in Santa Fe County, New Mexico
• Arroyo Seco (Alameda County), a watercourse in Alameda County, California
• Arroyo Seco (Los Angeles County), a watercourse in Los Angeles County, California
• Arroyo Seco (Salinas River), a watercourse in Monterey County, California
  • Arroyo Seco AVA, California wine region in Monterey County
• Arroyo Seco Creek, a watercourse in Sonoma County, California
• Arroyo Seco Junior High School, a middle school in Santa Clarita, California
• Arroyo Seco Parkway, the first California freeway
• Arroyo Seco Raceway, a paved racetrack near Deming, New Mexico

Other places

• Arroyo Seco, Santa Fe, Argentina
• Arroyo Seco, a barrio of Montevideo, Uruguay

Events

Arroyo Seco Fight, a skirmish between Texians and Comanche Indians in Texas in 1838.