Arylsulfatase (EC 3.1.6.1, sulfatase, nitrocatechol sulfatase, phenolsulfatase, phenylsulfatase, p-nitrophenyl sulfatase, arylsulfohydrolase, 4-methylumbelliferyl sulfatase, estrogen sulfatase) is a type of sulfatase enzyme with systematic name aryl-sulfate sulfohydrolase.^[1]^[2]^[3]^[4] This enzyme catalyses the following chemical reaction

an aryl sulfate + H₂O

\rightleftharpoons

a phenol + sulfate

Types include:

Arylsulfatase A (also known as "cerebroside-sulfatase")
Arylsulfatase B (also known as "N-acetylgalactosamine-4-sulfatase")
Steroid sulfatase (formerly known as "arylsulfatase C")
ARSC2
ARSD
ARSF
ARSG
ARSH
ARSI
ARSJ
ARSK
ARSL (formerly known as "arylsulfatase E", "ARSE")

References

^ Dodgson KS, Spencer B, Williams K (October 1956). "Studies on sulphatases. 13. The hydrolysis of substituted phenyl sulphates by the arylsulphatase of Alcaligenes metalcaligenes". The Biochemical Journal. 64 (2): 216–21. PMC 1199721. PMID 13363831.
^ Roy AB (1960). "The synthesis and hydrolysis of sulfate esters". Advances in Enzymology and Related Subjects of Biochemistry. 22: 205–35. PMID 13744184.
^ Roy AB (April 1976). "Sulphatases, lysosomes and disease". The Australian Journal of Experimental Biology and Medical Science. 54 (2): 111–35. doi:10.1038/icb.1976.13. PMID 13772.
^ Webb EC, Morrow PF (September 1959). "The activation of an arysulphatase from ox liver by chloride and other anions". The Biochemical Journal. 73 (1): 7–15. PMC 1197004. PMID 13843260.

Hydrolase: esterases (EC 3.1)

3.1.1: Carboxylic
ester hydrolases

Lipase

Phospholipase
- A1
- A2
- B

3.1.2: Thioesterase

3.1.3: Phosphatase

3.1.4:
Phosphodiesterase

3.1.6: Sulfatase

Nuclease (includes
deoxyribonuclease
and ribonuclease)

3.1.11-16:
Exonuclease

Exodeoxyribonuclease	RecBCD
Exoribonuclease	Oligonucleotidase

3.1.21-31:
Endonuclease

Endodeoxyribonuclease	Deoxyribonuclease I Deoxyribonuclease II Deoxyribonuclease IV Restriction enzyme;see ((Restriction enzyme)) UvrABC endonuclease
Endoribonuclease	RNase III Drosha: Microprocessor complex Dicer: RNA-induced silencing complex RNase H 1 2A 2B 2C RNase P RNase A RNase Z RNase E 1 2 3 4/5 RNase T1
either deoxy- or ribo-	Nuclease S1 Mung bean nuclease Serratia marcescens nuclease Micrococcal nuclease

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

See also

References