Atoltivimab
Monoclonal antibody
TypeWhole antibody
SourceHuman
TargetZaire ebolavirus glycoprotein
Clinical data
Pronunciationa" tol tiv' i mab
License data
Drug classMonoclonal antibody
ATC code
  • None
Identifiers
CAS Number
UNII
KEGG
Chemical and physical data
FormulaC6448H9954N1726O2002S44
Molar mass145097.28 g·mol−1

Atoltivimab is a Zaire ebolavirus glycoprotein-directed human monoclonal antibody that is part of the fixed-dose combination atoltivimab/maftivimab/odesivimab that is used for the treatment of Zaire ebolavirus (Ebola virus).[1][2][3]

References

  1. ^ "FDA Approves First Treatment for Ebola Virus". U.S. Food and Drug Administration (FDA) (Press release). 14 October 2020. Retrieved 14 October 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  2. ^ "Regeneron's Antibody Cocktail REGN-EB3 (Inmazeb) is First FDA-Approved Treatment for Ebola (Zaire Ebolavirus)". Regeneron Pharmaceuticals Inc. (Press release). 14 October 2020. Retrieved 14 October 2020.
  3. ^ Saxena D, Kaul G, Dasgupta A, Chopra S (August 2021). "Atoltivimab/maftivimab/odesivimab (Inmazeb) combination to treat infection caused by Zaire ebolavirus". Drugs of Today. 57 (8): 483–490. doi:10.1358/dot.2021.57.8.3280599. PMID 34405205. S2CID 237198823.

External links


Monoclonal antibodies for infectious disease and toxins
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