Bendazac
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration		Topical
ATC code
Identifiers
  • [(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.039.594 Edit this at Wikidata
Chemical and physical data
FormulaC16H14N2O3
Molar mass282.299 g·mol−1
3D model (JSmol)
  • O=C(O)COc2nn(c1ccccc12)Cc3ccccc3
  • InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) checkY
  • Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Bendazac (or bendazolic acid) is a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.[1]

Synthesis

Principal action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226 ; G. Palazzo, U.S. patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also

References

  1. ^ Balfour JA, Clissold SP (April 1990). "Bendazac lysine. A review of its pharmacological properties and therapeutic potential in the management of cataracts". Drugs. 39 (4): 575–96. doi:10.2165/00003495-199039040-00007. PMID 2190795. S2CID 46956362.



Categories