CABLES1
Identifiers
Aliases	CABLES1, CABL1, CABLES, HsT2563, IK3-1, Cdk5 and Abl enzyme substrate 1
External IDs	OMIM: 609194 MGI: 1927065 HomoloGene: 11097 GeneCards: CABLES1
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q11.2 Start 23,134,564 bp[1] End 23,260,470 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 A1 Start 11,972,277 bp[2] End 12,078,687 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in putamen nucleus accumbens caudate nucleus internal globus pallidus external globus pallidus amygdala entorhinal cortex cingulate gyrus sural nerve postcentral gyrus Top expressed in habenula cumulus cell lacrimal gland substantia nigra Paneth cell suprachiasmatic nucleus brown adipose tissue endocardial cushion left colon ascending aorta More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding Cellular component cytoplasm cytosol nucleus Biological process cell cycle regulation of cell cycle cell division nervous system development Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 91768 63955 Ensembl ENSG00000134508 ENSMUSG00000040957 UniProt Q8TDN4 Q9ESJ1 RefSeq (mRNA) NM_001100619 NM_001256438 NM_138375 NM_001146287 NM_022021 RefSeq (protein) NP_001094089 NP_001243367 NP_612384 NP_001139759 NP_071304 Location (UCSC) Chr 18: 23.13 – 23.26 Mb Chr 18: 11.97 – 12.08 Mb PubMed search [3] [4]
Wikidata
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CDK5 and ABL1 enzyme substrate 1 is a protein that in humans is encoded by the CABLES1 gene.^[5][6]

CABLES1 is a cyclin-dependent kinase (CDK)-binding protein that plays a role in proliferation and/or cell differentiation (Zukerberg et al., 2004).[supplied by OMIM].^[6] It is a tumor suppressor gene which losing it (by mutations, knockout, knockdown or inactivation) may lead to colorectal cancer CRC.^{[citation needed]}