|PDB||Ortholog search: PDBe RCSB |
|List of PDB id codes|
1K0M, 1K0N, 1K0O, 1RK4, 3O3T, 3P8W, 3P90, 3QR6, 3SWL, 3TGZ, 3UVH, 4IQA, 4JZQ, 4K0G, 4K0N
|Aliases||CLIC1, G6, NCC27, chloride intracellular channel 1, CL1C1, CLCNL1|
|External IDs||OMIM: 602872 MGI: 2148924 HomoloGene: 20343 GeneCards: CLIC1 |
|Location (UCSC)||Chr 6: 31.73 – 31.74 Mb||n/a|
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene.
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.
CLIC1 has been shown to interact with TRAPPC2.