Cytochrome P450, family 15, also known as CYP15, is an animal cytochrome P450 family found in insect genome,[1] involved in juvenile hormone biosynthesis.[2] The first gene identified in this family is the DpCYP15A1 from the Diploptera punctata (Pacific beetle cockroach), encodes an epoxidase of methyl farnesoate, a precursor of juvenile hormone, alone with its ortholog TcCYP15A1 in Tribolium castaneum (red flour beetle).[3]

References

  1. ^ Nelson, DR (November 1998). "Metazoan cytochrome P450 evolution". Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology. 121 (1–3): 15–22. doi:10.1016/s0742-8413(98)10027-0. PMID 9972448.
  2. ^ Daimon, T; Shinoda, T (January 2013). "Function, diversity, and application of insect juvenile hormone epoxidases (CYP15)". Biotechnology and Applied Biochemistry. 60 (1): 82–91. doi:10.1002/bab.1058. PMID 23586995. S2CID 25181420.
  3. ^ Minakuchi, C; Ishii, F; Washidu, Y; Ichikawa, A; Tanaka, T; Miura, K; Shinoda, T (September 2015). "Expressional and functional analysis of CYP15A1, a juvenile hormone epoxidase, in the red flour beetle Tribolium castaneum". Journal of Insect Physiology. 80: 61–70. doi:10.1016/j.jinsphys.2015.04.008. PMID 25921675.


Categories