Caprine arthritis encephalitis virus
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Pararnavirae
Phylum: Artverviricota
Class: Revtraviricetes
Order: Ortervirales
Family: Retroviridae
Genus: Lentivirus
Species:
Caprine arthritis encephalitis virus

Caprine arthritis encephalitis virus (CAEV) is a retrovirus which infects goats and cross-reacts immunologically with HIV,[1] due to being from the same family of viruses.[medical citation needed] CAEV cannot be transmitted to humans, including through the consumption of milk from an infected goat.[2] There is no evidence that CAEV can cure HIV in humans.[3]

CAEV is commonly transferred within the goat species by ingestion of colostrum or milk from an infected goat, and to a lesser extent, cross-species CAEV transfer by sheep is possible.[2][4]

Symptoms

CAEV adversely affects the immune system of its host, causing a disease known as caprine arthritis encephalitis. Common symptoms resulting from CAEV infection include arthritis, pneumonia, indurative mastitis, and encephalitis. One of the first and most common signs of CAEV infection is weight loss. However, many goats will not show any symptoms. Goats that do show symptoms may display swollen knee or carpal joints, lose body condition, and develop a rough hair coat. Pregnant and nursing goats will display a "hard udder", which is firm and swollen, and produce little milk.[2]

References

  1. ^ Tesoro-Cruz E, Hernández-González R, Kretschmer-Schmid R, Aguilar-Setién A (2003). "Cross-reactivity between caprine arthritis-encephalitis virus and type 1 human immunodeficiency virus". Arch. Med. Res. 34 (5): 362–6. doi:10.1016/j.arcmed.2003.08.001. PMID 14602501.
  2. ^ a b c "APHIS info sheet: Caprine arthritis encephalitis virus" (PDF). United States Department of Agriculture • Animal and Plant Health Inspection Service. May 2008. Archived from the original (PDF) on 2016-03-04. Retrieved 2017-03-12.
  3. ^ "Charlie Sheen Blasts Doctor Who Claims to Have Cured Him of HIV and Even Injected Himself with Star's Blood". PEOPLE.com. Retrieved 2016-02-27.
  4. ^ "Caprine Arthritis and Encephalitis" (PDF). colostate.edu. March 2007. Archived from the original (PDF) on 26 March 2018. Retrieved 5 November 2022.
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