The School of Seville loosely defines the artists that were active in Seville, Spain or were trained there by painters in the 16th and 17th centuries. During this time, Seville was enriched by the trade with the West Indies.

The most prominent painter to emerge from Seville, was Bartolome Esteban Murillo, who helped establish a local academy. Other painters who rose to prominence include Francisco Herrera the Elder, Luis de Vargas, and Alonso Cano.