Sir Charles Andrew Gladstone, 6th Baronet (28 October 1888 – 28 April 1968) was a Master at Eton College and a British baronet.

Gladstone was the son of the Reverend Stephen Edward Gladstone and Annie Crosthwaite Wilson, and the grandson of the former Prime Minister, William Ewart Gladstone.^[1] As a ten-year-old, he attended William Gladstone's state funeral.^[2] He was educated at Eton College and Christ Church, Oxford. He was a Master at Eton College from 1912 to 1946, he was commissioned a second lieutenant in the Territorial Force in 1912, attached to Eton's Officer Training Corps unit.^[3] He fought in World War I, and was attached to the Royal Flying Corps from April 1915.^[4] On being captured, he became a POW. After the war, he continued to serve with the Eton OTC until 1924 when he resigned his commission and was granted the honorary rank of lieutenant.^[5][6][7]

Gladstone married Isla Margaret Crum, the daughter of Sir Walter Erskine Crum, on 3 January 1925.^[8] They had six children, the oldest of whom was Sir Erskine William Gladstone of Fasque and Balfour, the 7th Baronet. Another son, Peter, was a noted naturalist.

Gladstone became a deputy lieutenant of Hampshire in 1929,^[9] and was the Vice-Lieutenant between 1948^[10] and 1968, and was a justice of the peace (JP) for Flintshire. He held the office of High Sheriff of Flintshire in 1951.^[11] In 1955 he was appointed a Commander of the Venerable Order of Saint John.^[12]

He succeeded to the title of 6th Baronet Gladstone, of Fasque and Balfour on 2 March 1967, following the death of his older brother, Sir Albert Charles Gladstone, the 5th Baronet.^[13] Having proved his claim to the baronetcy he did not use the title.

His son inherited the Baronetage under the appellation of Sir William Gladstone, 7th Baronet.