Charles Stuart, 12th Lord Blantyre, DL (21 December 1818 – 15 December 1900),^[1] styled Master of Blantyre from birth until 1830, was a Scottish nobleman and landowner with 14,100 acres (57 km²) of titled lands.^[2]

Born at Lennoxlove House, he was the second son of Maj.-Gen. Robert Stuart, 11th Lord Blantyre and his wife Frances Mary, the second daughter of the Hon. John Rodney, younger son of Admiral George Brydges Rodney, 1st Baron Rodney.^[3] In 1830 at the age of only twelve, he succeeded his father as Lord Blantyre.^[2] Stuart entered the British Army and was commissioned into the Grenadier Guards.^[4] He was appointed a Deputy Lieutenant of Renfrewshire in 1845 and was elected a Scottish representative peer in 1850.^[5]

On 4 October 1843 at Trentham, Staffordshire, Blantyre married Lady Evelyn, the second daughter of George Sutherland-Leveson-Gower, 2nd Duke of Sutherland, and had by her five daughters and a son, Walter, who predeceased him.^[6]

• Hon. Mary Stuart (15 September 1845 – 21 November 1910), unmarried.
• Hon. Ellen Stuart (31 August 1846 –19 April 1927), who married Sir David Baird, 3rd Baronet and together had six children. Their son inherited the Blantyre estates in 1900.
• Hon. Evelyn Stuart (24 June 1848 – 26 July 1888), who married Archibald Kennedy, 3rd Marquess of Ailsa. They had five children.
• Hon. Gertrude Stuart (11 November 1849 – 25 April 1935), married William Henry Gladstone MP, son of Prime Minister William Ewart Gladstone. They had two daughters, and one son, William Glynne Charles Gladstone.
• Capt. Hon. Walter Stuart, Master of Blantyre (17 July 1851 – 15 March 1895), unmarried. After expeditions in North America, he settled at Glenelg. A renowned figure in the Highlands, he predeceased his father without issue. A biography, The Master of Blantyre (1895) by Catherine Marsh, was published in his honour.^[7]

  

Lord Blantyre's wife died in Nice in 1869 and he survived her until 1900, dying aged 81 at Erskine House, which subsequently became Erskine Hospital (now a hotel, renamed Mar Hall).^[4] The Lordship of Blantyre became extinct on his death.