City mysteries are a 19th-century genre of popular novel, in which characters explore the secret underworlds of cities and reveal corruption and exploitation, depicting violence and deviant sexuality. They were popular in both Europe and the United States. All were inspired by the very successful serial novel The Mysteries of Paris (1842) by Eugène Sue, such as these:

• Les Vrais Mystères de Paris (1844) by Eugène François Vidocq
• Los misterios de Barcelona (1844) by Josep Nicasi Milà de la Roca
• Los misterios de Madrid: miscelánea de costumbres buenas y malas con viñetas y láminas á pedir de boca (1844) by Juan Martínez Villergas
• The Quaker City, or The Monks of Monk Hall (1845) by George Lippard
• Los Misterios del Plata (1846) by Juana Manso
• Venus in Boston (1849) by George Thompson
• City Crimes (1849) by George Thompson
• Life and Adventures of Jack Engle (1852) by Walt Whitman
• The Mysteries of Lisbon (1854) by Camilo Castelo Branco
• The Slums of Petersburg (1866) by Vsevolod Krestovsky
• Les Mystères de Marseille (1867) by Émile Zola
• The Mysteries of London (1844) by George W. M. Reynolds
• Les Mystères de Londres by Paul Féval
• Les Mystères de Lyon (featuring the Nyctalope) by Jean de La Hire
• I misteri di Napoli by Francesco Mastriani,
• Les Nouveaux Mystères de Paris by Léo Malet,
• Die Mysterien von Berlin by August Brass,
• Die Geheimnisse von Hamburg by Johann Wilhelm Christern,
• De Verborgenheden van Amsterdam by L. van Eikenhorst