| Coenzyme F420-1:γ-L-glutamate ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.3.2.34 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Coenzyme F420-1:γ-L-glutamate ligase (EC 6.3.2.34, F420:gamma-glutamyl ligase, CofE-AF, MJ0768, CofE) is an enzyme with systematic name L-glutamate:coenzyme F420-1 ligase (GDP-forming).[1][2] This enzyme catalyses the following chemical reaction
- GTP + coenzyme F420-1 + L-glutamate GDP + phosphate + coenzyme γ-F420-2
In some instances, this enzyme is fused with a coenzyme F420-0:L-glutamate ligase domain, so that the coenzyme F420-1 produced by the latter is quickly ligated to coenzyme F420-2. This enzyme is also able to serially add additional γ-glutamyl groups to F420-2, producing F420-3 and so on.[3]
