Greene began the 2015 season with the Single-ALansing Lugnuts, where he posted a 7–3 win–loss record, 3.88 ERA, and 65 strikeouts in 671⁄3 innings, before being promoted to the High-ADunedin Blue Jays.[2] He debuted for Dunedin on July 4 and took the loss, allowing four runs on nine hits.[5] On August 6, Greene set a career-high in strikeouts, with 10, while pitching seven shutout innings for Dunedin.[6] He was then promoted to the Double-ANew Hampshire Fisher Cats, and took the win in his debut on August 13, pitching six shutout innings against the Akron RubberDucks.[7] Greene made 26 starts in the 2015 season, posting a combined 12–7 record, 3.54 ERA, and 115 strikeouts in 1321⁄3 innings.[2]
Greene was invited to Major League spring training on January 12, 2016,[8] and reassigned to minor league camp on March 10.[9] Greene was assigned to the Dunedin Blue Jays to open the 2016 minor league season.[10] He was promoted to Double-A New Hampshire in early July, and pitched his first career complete game and shutout on July 26, defeating the Harrisburg Senators 1–0.[11] Greene made 27 total starts in 2016, and pitched to a 10–9 record, 3.51 ERA, and 99 strikeouts in a career-high 1461⁄3 innings.[2] After the 2016 season, the Blue Jays assigned Greene to the Mesa Solar Sox of the Arizona Fall League.[12] He made four starts for Mesa and struggled with his control, walking 11 batters in 10 total innings.[13] Greene spent all of 2017 with New Hampshire. In 1322⁄3 innings (26 games with 25 being starts), Greene went 5–10 with a 5.29 ERA and 92 strikeouts. He continued to struggle with his command, issuing 83 walks.[2] On November 20, 2017, Greene was added to Toronto's 40-man roster.[14]
On November 26, 2018, Greene was claimed off waivers by the Kansas City Royals.[20] Greene split the 2019 season between the Double-A Northwest Arkansas Naturals and the Triple-A Omaha Storm Chasers, recording a cumulative 4–9 record and 5.13 ERA in 29 appearances. Greene was designated for assignment by Kansas City on November 20, 2019.[21] Greene did not play in a game in 2020 due to the cancellation of the minor league season because of the COVID-19 pandemic.[22] He became a free agent on November 2, 2020.
Baltimore Orioles
On December 3, 2020, Greene signed a minor league contract with the Baltimore Orioles organization.[23] Greene was assigned to the Triple-A Norfolk Tides to begin the 2021 season. Greene posted a 1–3 record and 7.39 ERA in 9 appearances with Norfolk. On July 24, 2021, Greene was selected to the 40-man roster and promoted to the major leagues for the first time.[24] Greene made his MLB debut on July 27, pitching in relief against the Miami Marlins. He pitched two innings, giving up one run and striking out two.[25] On August 7, 2021, Greene was designated for assignment by the Orioles.[26]
Los Angeles Dodgers
Greene was claimed off waivers by the Los Angeles Dodgers on August 9, 2021.[27] He pitched in two games for the Dodgers, allowing two hits with no runs in two innings before he was designated for assignment on August 20.[28]
Baltimore Orioles
On August 23, 2021, Greene was reclaimed off waivers by the Orioles from the Dodgers.[29]
Greene pitched in 24 games in 2021, posting a 7.11 ERA with 26 strikeouts.
On March 14, 2022, Greene re-signed with the Orioles organization on a minor league contract that included an invitation to Spring Training.[30] He was released on June 2, 2022.
Diablos Rojos del México
On July 2, 2022, Greene signed with the Diablos Rojos del México of the Mexican League. In 12 games for México, he posted a 2–0 record and 6.00 ERA. In 2023, Greene made 30 appearances and registered a 4–3 record and 5.65 ERA with 38 strikeouts across 51.0 innings of work.
Greene is an avid surfer, and has also worked as a model. He is friends with actor Charlie Sheen, and made several minor appearances on the television series Anger Management.[33]
