This is an incomplete list of people who have served as Custos Rotulorum of Lancashire.

• Bartilmew Hesketh c.1535
• Sir John Holcroft 1547–1560
• Sir Richard Molyneux, 1st Baronet by 1598–1623
• Sir Richard Molyneux by 1627–1630
• James Stanley, 7th Earl of Derby by 1636
• Interregnum 1646–1660
• Richard Kirkby 1664–1681
• Caryll Molyneux, 3rd Viscount Molyneux c.1685–1689
• Hon Charles Gerard 1689–1701
• James Stanley, 10th Earl of Derby 1702–1710
• James Hamilton, 4th Duke of Hamilton 1710–1712
• vacant
• James Stanley, 10th Earl of Derby 1714–1736

The office was permanently joined with that of Lord Lieutenant of Lancashire before 1834.