Cynara is a genus of perennial plants.

Cynara may also refer to:

• A woman in Ernest Dowson's poem Non Sum Qualis eram Bonae Sub Regno Cynarae, first published in 1894
• Cynara (Delius), a musical setting by Frederick Delius of the poem
• Cynara (play), a 1930s London and Broadway production written by H. M. Harwood and Robert Gore-Browne
• Cynara (1932 film), based on the play and starring Ronald Colman
• Cynara (2023 film), a Canadian documentary directed by Sherien Barsoum
• "Cynara", a song by the industrial band Clan of Xymox
• Cynara Coomer, South African surgeon and medical journalist