DSG4
Identifiers
Aliases	DSG4, CDGF13, CDHF13, HYPT6, LAH, desmoglein 4
External IDs	OMIM: 607892 MGI: 2661061 HomoloGene: 65341 GeneCards: DSG4
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q12.1 Start 31,376,777 bp[1] End 31,414,912 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18 A2|18 11.35 cM Start 20,569,232 bp[2] End 20,604,878 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in duodenum skin of abdomen rectum vagina head mouth salivary gland minor salivary gland connective tissue adipose tissue Top expressed in lip zone of skin ileum jejunum placenta More reference expression data BioGPS n/a
Gene ontology Molecular function calcium ion binding metal ion binding Cellular component integral component of membrane cell junction desmosome membrane cornified envelope plasma membrane cell-cell junction Biological process hair follicle development cell adhesion BMP signaling pathway keratinocyte differentiation homophilic cell adhesion via plasma membrane adhesion molecules keratinization cornification cell-cell adhesion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 147409 16769 Ensembl ENSG00000175065 ENSMUSG00000001804 UniProt Q86SJ6 Q7TMD7 RefSeq (mRNA) NM_001134453 NM_177986 NM_181564 RefSeq (protein) NP_001127925 NP_817123 NP_853543 Location (UCSC) Chr 18: 31.38 – 31.41 Mb Chr 18: 20.57 – 20.6 Mb PubMed search [3] [4]
Wikidata
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Desmoglein-4 is a protein that in humans is encoded by the DSG4 gene.^[5][6]