Ribbon representation of human diamine oxidase.[1]
amiloride binding protein 1 (amine oxidase (copper-containing))
Identifiers
SymbolABP1
Alt. symbolsAOC1
NCBI gene26
HGNC80
OMIM104610
RefSeqNM_001091
UniProtP19801
Other data
EC number1.4.3.22
LocusChr. 7 q34-qter
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StructuresSwiss-model
DomainsInterPro

Amine oxidase (copper-containing), also known as histaminase or diamine oxidase, is an enzyme involved in the metabolism, oxidation, and inactivation of histamine in animals. Highest content is observed in the digestive tract and placenta.[2]

External links

References

  1. ^ PDB: 3HI7​; McGrath AP, Hilmer KM, Collyer CA, Shepard EM, Elmore BO, Brown DE, Dooley DM, Guss JM (Oct 2009). "Structure and inhibition of human diamine oxidase". Biochemistry. 48 (41): 9810–22. doi:10.1021/bi9014192. PMC 2791411. PMID 19764817.; rendered with PyMOL
  2. ^ Agúndez JA, Ayuso P, Cornejo-García JA, Blanca M, Torres MJ, Doña I, Salas M, Blanca-López N, Canto G, Rondon C, Campo P, Laguna JJ, Fernández J, Martínez C, García-Martín E (2012). "The diamine oxidase gene is associated with hypersensitivity response to non-steroidal anti-inflammatory drugs". PloS One. 7 (11): e47571. doi:10.1371/journal.pone.0047571. PMID 23152756.((cite journal)): CS1 maint: unflagged free DOI (link)


Enzymes involved in neurotransmission
Histamine receptor modulators
CH-NH2 oxidoreductases (EC 1.4) - primarily amino acid oxidoreductases
Categories