Diego Mendoza, or de Mendoza, may refer to:
- Diego Mendoza (born 1992), Argentine footballer
- Diego de Mendoza (1549–1562), Aztec Empire tlatoani or king
- Diego de Becerra-Mendoza (died 1533), Spanish captain murdered by mutineer Fortún Ximénez
This disambiguation page lists articles about people with the same name.
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