Diisopromine
Clinical data
ATC code
Identifiers
  • N,N-Diisopropyl-3,3-diphenylpropan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.025.230 Edit this at Wikidata
Chemical and physical data
FormulaC21H29N
Molar mass295.470 g·mol−1
3D model (JSmol)
  • c1ccccc1C(c2ccccc2)CCN(C(C)C)C(C)C
  • InChI=1S/C21H29N/c1-17(2)22(18(3)4)16-15-21(19-11-7-5-8-12-19)20-13-9-6-10-14-20/h5-14,17-18,21H,15-16H2,1-4H3 checkY
  • Key:YBJKOPHEJOMRMN-UHFFFAOYSA-N checkY
  (verify)

Diisopromine or disoprominum, usually as the hydrochloride salt, is a synthetic spasmolytic[1] which neutralizes spastic conditions of the biliary tract and of the sphincter of Oddi. It was discovered at Janssen Pharmaceutica in 1955. It is sold in South Africa under the brand name Agofell syrup as a mixture with sorbitol,[2] and elsewhere as Megabyl.[3]

See also

References

  1. ^ Milne GW (2018). "6187: Diisopromine Hydrochloride". Drugs: Synonyms and Properties. London: Routledge. ISBN 978-1-351-78989-9.
  2. ^ "AGOFELL® Syrup". South African electronic package inserts. Archived from the original on 20 September 2018. Retrieved 2 September 2015.
  3. ^ "Guide des medicaments". Doctissimo. Archived from the original on 20 September 2018. Retrieved 2 September 2015.



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