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((Short description|Milk produced by female donkeys))
((Copy edit|for=Lots of informalities, "today" and similar dated words, possible credulous/uncited reporting.|date=July 2023))
[[File:Foal and mother.jpg|thumb|Suckling donkey]]
'''Donkey milk''' (or '''ass milk''', or '''jenny milk''') is the [[milk]] from the domesticated [[donkey]] ''(Equus asinus)''. It has been used since antiquity for cosmetic purposes as well as infant nutrition.       

== History ==
((See also|Human–animal breastfeeding#Breastfeeding by animals of humans))
Donkey milk has been used by humans for alimentary and cosmetic purposes since [[Ancient Egypt|Egyptian]] antiquity;<ref>Uniacke-Lowe, T., 2011. Studies on equine milk and comparative studies on equine and bovine milk systems. PhD Thesis, University College Cork.</ref> doctors recommended it to treat several afflictions, due to its healing and cosmetic virtues.<ref name=":7">((Cite web |last1=Mansueto|first1=P.|last2=Carroccio|first2=Antonio|last3=D'Alcamo|first3=A.|last4=Seidita|first4=A.|last5=Iacono|first5=G.|last6=D'Alcamo|first6=A.|last7=Iacono|first7=S.|date=2012|title=Ass's milk in allergy to Cow's milk protein: a review|s2cid=79661818|language=en))</ref>

[[Hippocrates]] (460 – 370 BC), was the first to write of the medicinal use of donkey milk and prescribed it for numerous conditions including poisoning, fevers, infectious diseases, edema, healing wounds, nose bleeds, and liver trouble.<ref name=":1">((Cite web|url =http://journalfoodallergy.com/issue/v2n12013/Mansueto_et_al_v2n1.pdf|title =Ass's milk in allergy to Cow's milk protein: a review|url-status =dead|archive-url =https://web.archive.org/web/20160216071534/http://journalfoodallergy.com/issue/v2n12013/Mansueto_et_al_v2n1.pdf|archive-date =2016-02-16))</ref><ref name=":2">Hippocrates. The Genuine Work of Hippocrates. Vol. 1. Sydenham Society 1843</ref> In the Roman era donkey milk was a recognized remedy; [[Pliny the Elder]] (23 – 79 AD) in his encyclopedic work, ''[[Naturalis Historia]]'', wrote extensively about its health benefits, i.e. to fight fever, fatigue, eye strain, weakened teeth, face wrinkles, poisonings, ulcerations, asthma and certain gynecological troubles.<ref name=":3">Pliny the Elder. The Natural History. Book XXVIII “Remedies derived from living creatures”. John Bostock 1855.</ref> However, it was not until the Renaissance that the first real scientific consideration was given to donkey milk. [[Georges-Louis Leclerc, Comte de Buffon|Georges-Louis Leclerc the Comte de Buffon]] (1707–1788) mentions the benefits of donkey milk in his ''[[Histoire naturelle]]''<ref>Leclerc GL. L’Histoire naturelle, générale et particulière, avec la description du Cabinet du Roy. Tome Cinquième. P. Duménil 1835; 40.</ref> and [[Pauline Bonaparte]] (1780–1825), Napoleon's sister, is reported to have used donkey milk for skin care. In France in the nineteenth century, Dr. Parrot of the Hospital des Enfants Assistés spread the practice of bringing motherless babies directly to the donkey's nipple (Bullettin de l’Académie de médicine, 1882). Donkey's milk was sold until the [[20th century|twentieth century]] to feed orphaned infants and to cure delicate children, the sick and the elderly. For this reason, in Greece, Italy, Belgium, Germany, Switzerland many donkeys are born on farms.<ref>((Cite web|url = http://www.fedoa.unina.it/9122/1/costanzo_angela_25.PDF|title = Characterization of donkey milk proteins by a proteomic approach|date = 2013|publisher = Università di Napoli “Federico II”|last = Angela|first = Costanzo))</ref> In the twenty-first century, donkey milk is largely used in the manufacture of soaps and moisturizers, but new evidence shows its possible medical use, especially to treat, under the supervision of a doctor, infants and children with cow's milk protein allergy (CMPA)<ref name=":7" /> and with appropriate precautions such as a natural "formula" for infants.

== Production ==

The donkey is considered a seasonal [[Estrous cycle#Frequency|polyestrous]] animal, but the latitude in which the farm is located can greatly influence the reproduction cycle. The female is normally pregnant for about 12 months.<ref>Sewell, Sybil E. "Foaling out the Donkey Jennet," ''Alberta Donkey and Mule.com''. Web page accessed March 4, 2008</ref>

Donkey milk production differs greatly from that of conventional dairy species, especially in terms of milk supply, which is much more limited. The equid mammary gland has a low capacity (max 2.5 L) and a part of the milk production should be left to the foal and milking may be carried out two or three hours after separation from the foal.<ref>Doreau M (1991) Le lait de jument. INRA Productions Animales 4 :297–302.</ref> Donkeys should be milked three times a day from 20 to 90 days after foaling.<ref>Doreau M, Martin-Rosset W (2011) Animals that produce dairy foods – horse. In Encyclopaedia of dairy sciences (2nd ed.), Fuquay JW, Fox PF & McSweeney PLH, eds., San Diego, CA, USA: Academic Press, volume 1, pp. 358–364.</ref> A female gives between 0.5 and 1.3 litres of milk a day for about 6–7 months.((citation needed|date=June 2012)) The variability of donkey milk production is due to many factors, such as individual milkability, nutrition, genetics, management of reproduction, etc., in addition to milking management.<ref name="Salimei E 2012">((cite journal |doi=10.1016/j.idairyj.2011.11.008 |title=Equid milk for human consumption |journal=International Dairy Journal |volume=24 |issue=2 |pages=130–42 |year=2012 |last1=Salimei |first1=Elisabetta |last2=Fantuz |first2=Francesco ))</ref>

Generally a donkey farm (breeding) aimed at milk production is small, with some tens of heads and rarely more. In Europe, and specifically in Emilia Romagna (Italy) there is only one very large donkey farm with 800 head.

== Composition ==
[[File:E4t5hw45.jpg|thumb]]

=== Gross composition ===
Published data on donkey milk gross composition confirm the closer resemblance to breast milk for lactose, protein and ash levels when compared with cow, sheep and goat milk.<ref name="Salimei E 2012" /> Despite the high lactose content of donkey milk the average fat content is lower for this purpose. When used in infant nutrition, donkey milk is usually supplemented with vegetable oil (4&nbsp;mL per 100&nbsp;mL of milk) to conform to human milk energy.<ref name=":0">((cite journal |pmid=1593372 |year=1992 |last1=Iacono |first1=G |title=Use of ass' milk in multiple food allergy |journal=Journal of Pediatric Gastroenterology and Nutrition |volume=14 |issue=2 |pages=177–81 |last2=Carroccio |first2=A |last3=Cavataio |first3=F |last4=Montalto |first4=G |last5=Soresi |first5=M |last6=Balsamo |first6=V |doi=10.1097/00005176-199202000-00010 |s2cid=30551795 |doi-access=free ))</ref>

{| class="wikitable"
|+ Composition of donkey's, mare's, human and cow's milk (g/100 g)<ref name="pmid17369203">((cite journal |doi=10.3168/jds.2006-600 |pmid=17369203 |title=Composition, Physiochemical Properties, Nitrogen Fraction Distribution, and Amino Acid Profile of Donkey Milk |journal=Journal of Dairy Science |volume=90 |issue=4 |pages=1635–43 |year=2007 |last1=Guo |first1=H.Y |last2=Pang |first2=K |last3=Zhang |first3=X.Y |last4=Zhao |first4=L |last5=Chen |first5=S.W |last6=Dong |first6=M.L |last7=Ren |first7=F.Z |doi-access=free ))</ref>
|-
! Composition
! Donkey
! [[Mare milk|Mare]]
! [[breast milk|Human]]
! [[Cow milk|Cow]]
|-
| [[pH]] || 7.0 – 7.2 || 7.18 || 7.0 – 7.5 || 6.6 – 6.8
|-
| [[Protein]] g/100g || 1.5 – 1.8 || 1.5 – 2.8 || 0.9 – 1.7 || 3.1 – 3.8
|-
| [[Fat]] g/100g || 0.3 – 1.8  || 0.5 – 2.0 || 3.5 – 4.0 || 3.5 – 3.9
|-
| [[Lactose]] g/100g || 5.8 – 7.4 || 5.8 – 7.0 || 6.3 – 7.0 || 4.4 – 4.9
|-
| Total Solids (TS) g/100 g || 8.8–11.7 || 9.3–11.6 || 11.7–12.9 || 12.5–13.0
|-
| [[Casein]] Nitrogen (CN) g/100 g || 0.64–1.03 || 0.94–1.2 || 0.32–0.42 || 2.46–2.80
|-
| [[Whey protein]] g/100 g || 0.49–0.80 || 0.74–0.91 || 0.68–0.83 || 0.55–0.70
|-
| [[Non-protein nitrogen|NPN]] g/100 g || 0.18–0.41 || 0.17–0.35 || 0.26–0.32 || 0.1–0.19
|-
| [[Casein]] Nitrogen (CN) % || 47.28 || 50 || 26.06 || 77.23
|-
| [[Whey protein]] % || 36.96 || 38.79 || 53.52 || 17.54
|-
| [[Non-protein Nitrogen|NPN]] % || 15.76 || 11.21 || 20.42 || 5.23
|}

The casein to whey protein ratio in donkey milk was lower compared to the value on cow milk.

The non-protein nitrogen (NPN) accounts for an average of 16% of total nitrogen in donkey milk, is much closer than values reported for human milk (20%) but higher than those of domestic ruminants (5%).

The amino acid profile of the donkey milk proteins shows a very similar percentage of essential amino acids (36.7 e 38.2 g amino acid /100 g protein) than in human milk proteins (40.7 g amino acid /100 g protein).<ref name="pmid17369203" />

=== Functional and bioactive components ===
Among the functional proteins detected in donkey milk, there are molecules active in antimicrobial protection such as lysozyme and lactoferrin. The lactoferrin content of donkey milk is intermediate between the lower values of cow milk and the higher values of human milk. Lactoferrin inhibits the growth of iron-dependent bacteria in the gastrointestinal tract. This inhibits certain organisms, such as coliforms and yeast, that require iron. Lysozyme in donkey milk is present in large amounts, indeed ranges from 1.0&nbsp;mg/mL to 4&nbsp;mg/mL, depending on the analytical method used (chemical or microbiological);<ref name="Salimei E 2012" /> this substance is present also in human (0.12&nbsp;mg/mL) but only in trace amounts in cow and goat milk.<ref>((Cite web|url = https://www.soas.ac.uk/history/conferences/donkey-conference-2012//archive-of-previous-papers/file86174.pdf|title = Nutritional qualities of donkey milk|access-date = 2016-02-11|archive-date = 2021-01-18|archive-url = https://web.archive.org/web/20210118181627/https://www.soas.ac.uk/history/conferences/donkey-conference-2012/archive-of-previous-papers/file86174.pdf|url-status = dead))</ref> Lysozyme in donkey milk is highly thermo-stable and is very resistant to acid and protease and may play a significant role in the intestinal immune response.<ref>((cite journal |doi=10.1016/j.idairyj.2010.10.008 |title=Antimicrobial effect of donkeys' milk digested in vitro with human gastrointestinal enzymes |journal=International Dairy Journal |volume=21 |issue=3 |pages=158–65 |year=2011 |last1=Tidona |first1=Flavio |last2=Sekse |first2=Camilla |last3=Criscione |first3=Andrea |last4=Jacobsen |first4=Morten |last5=Bordonaro |first5=Salvatore |last6=Marletta |first6=Donata |last7=Vegarud |first7=Gerd Elisabeth ))</ref>

In donkey mammary secretion, defatted or not, growth factors and hormones have also been determined. In detail, donkey mammary secretions contain human-like leptin at levels close to human milk (3.35 e 5.32&nbsp;ng/mL milk).<ref name="Salimei E 2012" /> The bioactive peptides insulin like growth factor 1, ghrelin and triiodothyronine were also found in frozen donkey milk. These molecules, and many others present in human milk, are increasingly receiving attention from a nutraceutical point of view because of their potential direct role in regulating food intake, metabolism, and infant body condition.<ref name="Salimei E 2012" />

== Nutritional use ==

=== Natural hypoallergenic milk for infants with cows' milk protein allergy ===
Pasteurized donkey milk is used as a natural hypoallergenic milk,<ref name=":4">((cite journal|last1=Fiocchi|first1=Alessandro|last2=Brozek|first2=Jan|last3=Schünemann|first3=Holger|last4=Bahna|first4=Sami L|last5=von Berg|first5=Andrea|last6=Beyer|first6=Kirsten|last7=Bozzola|first7=Martin|last8=Bradsher|first8=Julia|last9=Compalati|first9=Enrico|last10=Ebisawa|first10=Motohiro|last11=Guzman|first11=Maria Antonieta|year=2010|title=World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cowʼs Milk Allergy (DRACMA) Guidelines|journal=World Allergy Organization Journal|volume=3|issue=4|pages=57–161|doi=10.1097/WOX.0b013e3181defeb9|pmc=3488907|pmid=23268426|last22=Vieths|first21=Luigi|last21=Terracciano|first20=Airton|last20=Stein|first19=Hugh|last19=Sampson|first18=Fabienne|last18=Rancé|first17=Alberto|last17=Martelli|first16=Massimo|last16=Landi|first15=Gideon|last15=Lack|first14=Paul|last14=Keith|first13=Ralf G|last13=Heine|first12=Haiqi|last12=Li|first22=Stefan))</ref> because it is tolerated by about 90% of infants with food allergies, e.g., cows' milk protein allergy (CMPA), a common food allergy in childhood with a prevalence of approximately 3% during the first 3 years of life.<ref name="Salimei E 2012" /> However the infants tolerance of donkey milk must be evaluated first subjectively, under medical supervision and after carrying out specific allergy tests. As natural hypoallergenic formula it is preferred over those of soy or produced from protein hydrolysates because has a pleasant taste and does not cause allergies in some people who also have allergic reactions to soy proteins or protein hydrolysates

=== Natural infants "formula" ===
[[File:Direct udder nursing 1895.jpg|thumb|Donkeys suckling children in a French institution, 1895. [[Human–animal breastfeeding#Breastfeeding by animals of humans|Direct udder nursing]] became widespread in Europe once the risk of infected wet nurses was understood.]]
Donkey's milk is similar to human milk for its lactose, proteins, minerals, amino-acid content.

In terms of energy despite the high lactose content of donkey milk the average fat content is lower if used predominantly before weaning.

When used in infant nutrition before weaning, due to its low fat content to mimic breast milk, like all infant formulas, donkey milk should be integrated with a source of fat;<ref name=":0" /> particular attention must also be given to essential fatty acids.<ref name=":8">((Cite journal|last1=Huffman|first1=Sandra L.|last2=Harika|first2=Rajwinder K.|last3=Eilander|first3=Ans|last4=Osendarp|first4=Saskia J. M.|date=2011|title=Essential fats: how do they affect growth and development of infants and young children in developing countries? A literature review|url=|journal=Maternal & Child Nutrition|language=en|volume=7|issue=s3|pages=44–65|doi=10.1111/j.1740-8709.2011.00356.x|issn=1740-8709|pmc=6860654|pmid=21929635))</ref> Omega‐3 and omega‐6 fatty acids, particularly docosahexaenoic acid (DHA), are known to play an essential role in the development of the brain and retina. Intakes in pregnancy and early life affect growth and cognitive performance later in childhood,ensuring adequate intakes of fat, essential fatty acids and especially DHA through these life stages is crucial, cost effective dietary sources of these fatty acids are needed to ensure adequate essential fatty acid and DHA intakes in these populations.<ref name=":8" /> The integration of these substances can take place with supplements of essential fatty acids (omega-3; omega-6) and vegetable oil certified for babies; this aspect is important to exclude the presence of spores that can pass the gastric mucosa in the first 4 months. For children who are not allergic to cow or goat milk, a part of fat can be compensated naturally by adding 1-2% of cow or goat butter. In any case, the integration of fats and essential fats can be done through the integration of donkey milk with artificial formulas for infants.

From the point of view of hygienic-sanitary safety, like all milks, donkey milk and its ingredients must be pasteurized before taking; the process of pasteurizing donkey milk deactivates bacterial and viral contaminants.

Donkey milk contains immune-enhancing compounds (in particular lysozyme and lactoferrin) to help protect infants from disease. In addition, the flavour and appearance of donkey milk have been found to be attractive to children.<ref name="Salimei E 2012" />

=== Diet supplement ===
Donkey's milk is recommended for countering stomach acid, promoting the growth of intestinal flora, calming coughs and pertussis (a.k.a. whooping cough), and for use in the treatment of immune-mediated disorders.<ref>((Cite web|title=L'asino e la sua storia|url=https://www.georgofili.info/contenuti/lasino-e-la-sua-storia/2501|url-status=live|archive-url=https://web.archive.org/web/20211213154314/https://www.georgofili.info/contenuti/lasino-e-la-sua-storia/2501 |archive-date=2021-12-13 ))</ref>

== Commercial forms ==

=== Raw donkey milk ===
Donkey milk milked and cooled to refrigeration temperature. According to European legislation, like all milks of animal origin, it must be pasteurized before being used, i.e. it must be cooked at home up to about 90 °C for at least 2 minutes.

Raw milk can be kept for 3 days at refrigerator temperature starting from the day of milking. To prolong conservation, raw milk can be frozen for up to 2-3 months. In any case, it must be thawed in the refrigerator and pasteurized before use.

=== Pasteurized donkey milk ===
Donkey milk is pasteurized in a closed circuit of pasteurization and bottling (aseptic) at at least 72&nbsp;°C for 15 seconds or equivalent times and temperatures. In case of pasteurization in discontinuous systems, the temperature must be higher depending on the method used and the type of plant and destination.

=== Freeze drying (lyophilized) ===
Donkey milk can be [[freeze dried]] to preserve the biological quality of the milk, and so preserve its nutritional, functional and cosmetic properties. This is possible because in freeze drying the milk is frozen and brought under vacuum at low temperatures. During this process the water is removed by sublimation. The result is approximately ten percent of dry matter that is called lyophilized (or freeze dried) donkey milk. This powder is easy to reconstitute. The lyophilized product has to be packaged without any oxygen. It has a shelf life of two years. Normally it is produced from pasteurized donkey milk so it is ready to use.

Concluding, the treatment of lyophilization (freeze dried) of donkey's milk demonstrated that the natural colour, flavours, nutrients, bioactive substances of the fresh donkey milk are retained.<ref>((Cite web|title=Effects of Lyophilization and Use of Probiotics on Donkey's Milk Nutritional Characteristics|url=http://agris.fao.org/agris-search/search.do?recordID=US201400145388|access-date=2016-02-13|website=agris.fao.org))</ref> Instead, with the spray-drying method, another way to dry products, the milk is being heated whereby vitamins and other important bioactive substances will get lost. In addition Freeze-dried do not require chemical preservatives and can be either consumed directly or re hydrated easily. However, this method for its high costs is practiced only by a few companies.

This product it is easy to find in Italy and Europa , where it was for the first time put on the market.((citation needed|date=February 2021))

=== Fermented donkey milk (kumis) ===
The use of fermented equid milk is an ancient tradition in central Asia, like [[kumis]]<ref>Uniacke-Lowe, T. (2011). Koumiss. In J. W. Fuquay, P. F. Fox, & P. L. H. McSweeney (Eds.) (2nd ed.). Encyclopedia of dairy sciences, Vol. 2 (pp. 512e517) San Diego, CA, USA: Academic Press.</ref> or [[Kumis|airag]], a fermented mares milk very popular in Asia and Russia; but there are also traditional variants made from donkey milk.<ref name=":5">((Cite web|title=Discussion on Kumiss|url=http://www.diningwiththekhan.com/discussion-on-kumiss.html|access-date=2016-02-13|website=Dining with the Khan))</ref>

In Mongolia, where kumis is the national drink, people have a saying that ‘kumys cures 40 diseases’.<ref>((cite journal|last1=Levine|first1=Marsha A|year=2015|title=Eating horses: The evolutionary significance of hippophagy|journal=Antiquity|volume=72|issue=275|pages=90–100|doi=10.1017/S0003598X00086300|s2cid=162715115))</ref>

== Cosmetic use ==

=== Cosmetics with donkey milk ===
In recent years, the cosmetic industry is mainly focused towards products made with natural ingredients and it is oriented to a sustainable consumption. Because of their natural origin, milk components correspond in many fields to the needs of cosmetology.<ref name=":6">((cite book|last1=Cosentino|first1=Carlo|title=The Sustainability of Agro-Food and Natural Resource Systems in the Mediterranean Basin|last2=Paolino|first2=Rosanna|last3=Musto|first3=Mauro|last4=Freschi|first4=Pierangelo|year=2015|isbn=978-3-319-16356-7|pages=113–32|chapter=Innovative Use of Jenny Milk from Sustainable Rearing|doi=10.1007/978-3-319-16357-4_8))</ref>

Recent scientific study on a cream containing of lyophilized donkey milk showed different benefits for the skin. These results are related to the effectiveness of donkey milk components like proteins, minerals, vitamins, essential fatty acids, bioactive enzyme and coenzyme which allow the skin a balanced nourishment and a proper hydration. In particular vitamin C content in donkey milk is almost 4 times more of cow's milk. Donkey milk contain more lactoferrin of cow milk and a considerable mounts of lysozyme, from 1.0&nbsp;mg/mL to 4&nbsp;mg/mL (depending on the analytical method used: chemical or microbiological), instead cow's milk only traces. For this reason, it has the potentiality, when properly formulated, to reduce problem skin with eczema, acne, psoriasis and herpes and properties in calming the irritation symptoms as reported by some authors.

Some authors have preliminarily evaluated whether the use of a face cream made from donkey milk affected the perception of some sensory aspects. The results showed that treated cream resulted appreciated by dry skin consumers for the following sensory aspects: spreadability, total appearance, smoothness, moisturisation and total effectiveness . The overall judgement also resulted highest for face cream made with donkey milk.<ref name=":6" /><ref>((cite journal|last1=Cosentino|first1=C|last2=Freschi|first2=P|last3=Valentini|first3=R|year=2013|title=Market sustainability analysis of jenny milk cosmetics|journal=Emirates Journal of Food and Agriculture|volume=25|issue=8|pages=635–40|doi=10.9755/ejfa.v25i8.16093|doi-access=free|hdl=11563/44833|hdl-access=free))</ref>

Today, donkey milk is still used in the manufacture of [[soap]]s and creams.<ref name="DonkeyMilkSoap">[http://donkeymilksoap.com/index.php/en/donkey-milk-soap-products-shops-by-country DonkeyMilkSoap.com] A list of online shops selling donkey milk soap.</ref>

=== History ===
It is said that [[Cleopatra VII|Cleopatra]], Queen of [[Ancient Egypt]], took baths in donkey milk to preserve the beauty and youth of her skin. Legend has it that no less than 700 donkeys were needed to provide the quantity of milk necessary for her daily bath.<ref name=":1" /><ref name=":2" /><ref name="Chappez 2000">((cite book|last=Chappez|first=Gérard|url=https://books.google.com/books?id=klMMY9I934YC|title=L'âne: histoire, mythe et réalité : tiré de Bougres d'ânes|publisher=Editions Cabedita|year=2000|isbn=978-2-88295-278-3|pages=56–57))</ref><ref>((Cite web|title=» Why did Cleopatra supposedly bathe in sour donkey milk? Office for Science and Society|url=https://www.mcgill.ca/oss/article/science-science-everywhere-you-asked/why-did-cleopatra-supposedly-bathe-sour-donkey-milk/|access-date=2017-09-01|website=blogs.mcgill.ca|language=en-US))</ref>

This was also the case of [[Poppaea Sabina]] (30–65), second wife of [[Roman Emperor]] [[Nero]], who is referred to in [[Pliny the Elder|Pliny]]'s description of the ass milk virtues for the skin:

''"It is generally believed that ass milk effaces wrinkles in the face, renders the skin more delicate, and preserves its whiteness: and it is a well-known fact, that some women are in the habit of washing their face with it seven times daily, strictly observing that number. Poppaea, the wife of the Emperor Nero, was the first to practise this; indeed, she had sitting-baths, prepared solely with ass milk, for which purpose whole troops of she- asses used to attend her on her journeys."''<ref name=":3" /><ref name="extension 2008">((cite web|date=2008-07-15|title=L'âne le meilleur ami de l'homme|url=http://www.lextension.com/index.php?page=theme&idActu=9810&theme=Economie%20durable|url-status=live|archive-url=https://web.archive.org/web/20090324134629/http://www.lextension.com/index.php?page=theme&idActu=9810&theme=Economie%20durable|archive-date=24 March 2009|access-date=2009-03-20|publisher=L'Extension.com))</ref>

The Roman poet Ovid (43 BC. – 18 AD.) also in his poem ''Medicamina Faciei Femineae'', suggest beauty masks made with donkey milk.

[[Pauline Bonaparte]] (1780–1825), Napoleon's sister, is also reported to have used ass milk for her skin's health care.<ref name=":1" /><ref name="extension 2008" />

=== Traditional Medicine ===
((ref improve section|date=July 2023))
Much of the "medicinal" use of equid milk (donkey and mare) is based on tradition. The accuracy and clarity of the results that can be obtained with the scientific method are certainly to be appreciated, however, scientific studies on equid milk are often lacking regarding the beneficial effects towards certain pathologies. Popular medicine or traditional medicine is defined as one that follows traditions and not the scientific method and is the set of medical practices prior to the advent of industrial medicine (founded with the establishment of large pharmaceutical companies).The scientific method has weaknesses and limitations as much as any other method, so in the meantime the data that derives from cultural experience should not be underestimated. Many of these practices have become rooted in popular knowledge and tradition. The first written documents reporting the nutritional and "curative" effects of equine milk date back to around 2000 years ago. 

In fact, already Herodotus in the 5th century B.C. mentions it as a nutritious drink. [[Hippocrates]] (460–370 BC.), the father of medicine, was the first to describe the medicinal virtues of donkey milk. He prescribed donkey milk for numerous ailments, such as liver problems, edemas, nosebleeds, poisonings, infectious diseases, the healing of sores, and fevers. In Roman times, donkey milk was used as a universal remedy: [[Pliny the Elder]] (23–79 AD), in his encyclopedic work [[Natural History (Pliny)|Naturalis Historia]], has widely described its health benefits. In particular, Pliny writes about 54 medicinal uses of donkey milk, ranging (spacing) from its use as an anti-venom or as a relief for external irritations (itching) to the use of it in a pomade (ointment) for the eyes. He states that donkey milk is the most effective as a medicine, followed by cow's milk, and then goat's milk. During the Renaissance, donkey milk was the subject of a first real scientific consideration by the wise men of the time, when Francis I, king of France, on the advice of his doctors, used donkey milk to recover from a long illness. There are various testimonials concerning the effectiveness of donkey milk. The famous French naturalist [[Georges-Louis Leclerc, Comte de Buffon|Georges-Louis Leclerc]] (1707–1788) underlined the benefits of donkey milk in his ''[[Histoire Naturelle]]''.<ref>((Cite journal |last1=Bertino |first1=Enrico |last2=Agosti |first2=Massimo |last3=Peila |first3=Chiara |last4=Corridori |first4=Marinella |last5=Pintus |first5=Roberta |last6=Fanos |first6=Vassilios |date=2022-01-18 |title=The Donkey Milk in Infant Nutrition |journal=Nutrients |volume=14 |issue=3 |pages=403 |doi=10.3390/nu14030403 |issn=2072-6643 |pmc=8840189 |pmid=35276763 |doi-access=free ))</ref>

Some effects have also been supported by systematic and scientific studies starting from the mid-1800s, especially by Russian doctors.

It is worth remembering that donkey and mare's milk are very similar therefore it is assumed that we have similar properties therefore for knowledge based on tradition we often speak indistinctly of donkey and mare's milk (equid milk).

The beneficial effects of equine milk, from the first historical sources to the present day, are aimed at:
* Lungs and the entire respiratory system
* Entire digestive system including the liver
* Metabolism
* Skin, directly and indirectly through the intestine
* Hematopoietic organs

It was generally described as a food capable of regenerating a weakened, emaciated, impoverished organism in an unusually short time, allowing the body to achieve better resistance. It was used by the Asian (Mongolian) equestrian peoples often as the only source of food for long periods of time and during high physical exertion, without the body developing symptoms of deficiency. Under [[Genghis Khan|Genghis-chan]], the Mongols established the largest world empire ever. They moved on their horses across the steppes, deserts and mountains and covered distances that required weeks of travel in a few days and for long periods they lived mainly on the milk of their mares, both fresh and fermented (kumyss). Around 1850, various Russian doctors observed the habits of the shepherds of the Baskirian steppe. They reported that the Basic and Tatars spent the winter in very unfavorable environmental conditions, with temperatures down to minus 60°C, severe winter storms, and very little or no food. Weakened nomads regained their strength unusually quickly as soon as they fed on mare's milk. Russian doctors observed in the 19th century that tuberculosis was practically non-existent among the steppe nomads. Doctors attributed it to fermented mare's milk as the staple food of the steppe people. When this became known in Russia, a migration of tuberculosis patients from Russia to the Asian steppes began. The treatment was initially "wild", without medical supervision. From 1850 the first sanatoriums were founded and treatments were oriented along systematic, medical-scientific lines, however the importance of Kumyss treatment of tuberculosis in Russia lasted until about 1970, then it was gradually replaced by modern medicine. However, Kumys' treatment was the most effective [[tuberculosis]] therapy for many years. Treatment with Kumys & mare's milk has been extended to other diseases in Russia and Kazakhstan over the decades: non-tuberculous diseases of the respiratory system (e.g. pneumonia, all forms of bronchitis), diseases of the digestive system (inflammations and stomach and duodenal ulcers, inflammatory bowel disease), liver disease (all forms of liver inflammation e.g. hepatitis up to cirrhosis of the liver, dyslipidaemia), various forms of anemia, all forms of debilitating and exhausting diseases, irrespective of cause (e.g. major operations, cancer, burns, immunodeficiencies) as well as more rare and to a lesser extent concomitant with surgical, gynecological, urological diseases, both in adults and children. Language barriers and cultural differences still prevent an exchange between the Western cultural area and these cultures today, however Russia and Kazakhstan are still conducting scientific research on the effects of equine milk and kumyss on humans.<ref>((Cite web |title=Stutenmilch. - das unbekannte Lebenselixier. (Herausgeber) - PDF Kostenfreier Download |url=https://docplayer.org/40788919-Stutenmilch-das-unbekannte-lebenselixier-herausgeber.html |access-date=2023-05-18 |website=docplayer.org))</ref>((Unreliable source?|reason=Possibly dissertation or other primary/non-peer-reviewed work.|date=July 2023))<ref>((Cite web |last=Hackelberg |first=Alexander |title=ZUR VERWENDBARKEIT VON STUTENMILCH, KUMYB UND ESELMILCH ALS DIÄTETIKA UND HEILMITTEL unter besonderer Berücksichtigung der Bedürfnisse des Säuglings und des Frühgeborenen (USE OF MARE'S MILK, KUMYS AND DONKEY'S MILK AS DIETETIC AND MEDICINAL PRODUCTS, WITH SPECIAL NOTE TO THE NEEDS OF THE INFANT AND THE PREMATURE BABY) |url=http://avtorskie.by/materialy/files/alexander-hackelberg.pdf |journal=))</ref>((Unreliable source?|reason=Possibly dissertation or other primary/non-peer-reviewed work.|date=July 2023))

Postnikov, a Russian doctor who dedicated his entire life to the research and use of horse milk in the mid-19th century , summed up its effects in three words:
* Nourishes: gives the body the ability to better absorb and use food.
* Strengthens: strengthens and stimulates the functional activity of the organs.
* Modification: change, renew the metabolism functions in the body towards healthy and normal.

== References ==
((Reflist))

((Milk by provenance))
((Donkeys))
((Authority control))

[[Category:Milk by animal]]
[[Category:Donkeys]]

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