This article relies largely or entirely on a single source. Relevant discussion may be found on the talk page. Please help improve this article by introducing citations to additional sources.Find sources: "EA-2054" – news · newspapers · books · scholar · JSTOR (September 2018)
EA-2054
Names
Preferred IUPAC name
N,N,N-Trimethyl-3-({[(propan-2-yl)oxy](methylphosphonoyl)}oxy)-5-{3-[3-(trimethylazaniumyl)phenoxy]propoxy}anilinium bis(tetraphenylboranuide)
Identifiers
3D model (JSmol)
  • InChI=1S/C25H41N2O5P.2C24H20B/c1-20(2)31-33(9,28)32-25-18-22(27(6,7)8)17-24(19-25)30-15-11-14-29-23-13-10-12-21(16-23)26(3,4)5;2*1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h10,12-13,16-20H,11,14-15H2,1-9H3;2*1-20H/q+2;2*-1
    Key: JVVQIPCTBBUOET-UHFFFAOYSA-N
  • [B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.[B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.CC(C)OP(=O)(C)Oc5cc([N+](C)(C)C)cc(c5)OCCCOc6cccc(c6)[N+](C)(C)C
Properties
C73H81B2N2O5P
Molar mass 1119.05 g·mol−1
Appearance Solid
Melting point 97–100 °C (207–212 °F; 370–373 K)
Insoluble
Solubility Soluble in acetone
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Extremely toxic
Lethal dose or concentration (LD, LC):
74 μg/kg (Rats, IV)
15 μg/kg (Rabbits, IV)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

EA-2054 is an extremely toxic organophosphate nerve agent. It is an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment.[1]

See also

References

  1. ^ "Toxic phosphorus compounds".
Categories