EIF2B5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF2B5, CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, eukaryotic translation initiation factor 2B subunit epsilon
External IDsOMIM: 603945 MGI: 2446176 HomoloGene: 2903 GeneCards: EIF2B5
Orthologs
SpeciesHumanMouse
Entrez

8893

224045

Ensembl

ENSG00000145191

ENSMUSG00000003235

UniProt

Q13144

Q8CHW4

RefSeq (mRNA)

NM_003907

NM_172265

RefSeq (protein)

NP_003898

NP_758469

Location (UCSC)Chr 3: 184.14 – 184.15 MbChr 16: 20.32 – 20.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Translation initiation factor eIF-2B subunit epsilon is a protein that in humans is encoded by the EIF2B5 gene.[5][6]

Interactions

EIF2B5 has been shown to interact with EIF2B2[7] and EIF2B1.[7][8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145191 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003235 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Asuru AI, Mellor H, Thomas NS, Yu L, Chen JJ, Crosby JS, Hartson SD, Kimball SR, Jefferson LS, Matts RL (Jul 1996). "Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human". Biochimica et Biophysica Acta. 1307 (3): 309–17. doi:10.1016/0167-4781(96)00054-1. PMID 8688466.
  6. ^ "Entrez Gene: EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa".
  7. ^ a b Anthony TG, Fabian JR, Kimball SR, Jefferson LS (Jun 2000). "Identification of domains within the epsilon-subunit of the translation initiation factor eIF2B that are necessary for guanine nucleotide exchange activity and eIF2B holoprotein formation". Biochimica et Biophysica Acta. 1492 (1): 56–62. doi:10.1016/S0167-4781(00)00062-2. PMID 10858531.
  8. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

Further reading


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