EIF3I
Identifiers
AliasesEIF3I, EIF3S2, PRO2242, TRIP-1, TRIP1, eIF3-beta, eIF3-p36, eukaryotic translation initiation factor 3 subunit I
External IDsOMIM: 603911 MGI: 1860763 HomoloGene: 2786 GeneCards: EIF3I
Orthologs
SpeciesHumanMouse
Entrez

8668

54709

Ensembl

ENSG00000084623

ENSMUSG00000028798

UniProt

Q13347

Q9QZD9

RefSeq (mRNA)

NM_003757
NM_001394168

NM_018799

RefSeq (protein)

NP_003748

NP_061269

Location (UCSC)Chr 1: 32.22 – 32.25 MbChr 4: 129.49 – 129.49 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Eukaryotic translation initiation factor 3 subunit I (eIF3i) is a protein that in humans is encoded by the EIF3I gene.[5][6][7]

Interactions

eIF3i has been shown to interact with TGF beta 1[8] and eIF3a.[6][9][10]

See also

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000084623 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028798 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Chen RH, Miettinen PJ, Maruoka EM, Choy L, Derynck R (Nov 1995). "A WD-domain protein that is associated with and phosphorylated by the type II TGF-beta receptor". Nature. 377 (6549): 548–52. Bibcode:1995Natur.377..548C. doi:10.1038/377548a0. PMID 7566156. S2CID 4341262.
  6. ^ a b Asano K, Kinzy TG, Merrick WC, Hershey JW (Feb 1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3". J. Biol. Chem. 272 (2): 1101–9. doi:10.1074/jbc.272.2.1101. PMID 8995409.
  7. ^ "Entrez Gene: EIF3S2 eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa".
  8. ^ Choy L, Derynck R (Nov 1998). "The type II transforming growth factor (TGF)-beta receptor-interacting protein TRIP-1 acts as a modulator of the TGF-beta response". J. Biol. Chem. 273 (47): 31455–62. doi:10.1074/jbc.273.47.31455. PMID 9813058.
  9. ^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
  10. ^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". Eur. J. Biochem. 270 (20): 4133–9. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.

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