EcoCyc

Content
Description	comprehensive database of Escherichia coli biology.
Organisms	Escherichia coli
Contact
Research center	SRI International
Laboratory	SRI International
Authors	Peter Karp et al[1]
Primary citation	Keseler & al. (2011)[1]
Access
Website	ecocyc.org

In bioinformatics EcoCyc is a biological database for the bacterium Escherichia coli K-12. The EcoCyc project performs literature-based curation of the E. coli genome, and of E. coli transcriptional regulation, transporters, and metabolic pathways. EcoCyc contains written summaries of E. coli genes, distilled from over 36,000 scientific articles. EcoCyc is also a description of the genome and cellular networks of E. coli that supports scientists to carry out computational analyses.^[2]

Data objects in the EcoCyc database describe each E. coli gene and gene product. Database objects also describe molecular interactions, including metabolic pathways, transport events, and the regulation of gene expression. EcoCyc provides several genome-scale visualization tools to aid in the analysis of omics data, such as by painting gene expression or metabolomics data onto the full regulatory network of E. coli.^{[citation needed]}

EcoCyc can be accessed through the EcoCyc web site, as a set of downloadable files, and in conjunction with the Pathway Tools software that can be installed locally on Macintosh, PC/Windows, and PC/Linux computers. The downloadable software provides capabilities that go well beyond the web version of EcoCyc.^{[citation needed]}