Edmund Brydges, 2nd Baron Chandos (before 1522 – 11 March 1573) was an English peer and politician. He was a Knight of the Garter, Baron Chandos, Lord Lieutenant of Gloucestershire and Vice-Admiral of Gloucestershire.
He was the eldest son and heir of John Brydges, 1st Baron Chandos and Elizabeth Grey, daughter of Edmund Grey, 9th Lord Grey of Wilton, and Florence Hastings. He succeeded to the barony on 12 April 1557 upon the death of his father.
He was elected Member of Parliament for Wootton Bassett in 1545. He was made a Knight of the Garter in 1572.
He was the first husband of Dorothy Bray, who, several years prior to their marriage in 1546, had engaged in a love affair at court with William Parr, 1st Marquess of Northampton. Chandos and Dorothy together had five children.
Chandos died in 1573 and was succeeded by his eldest son Giles Brydges, 3rd Baron Chandos.