Ertumaxomab
Monoclonal antibody
TypeTrifunctional antibody
SourceRat/mouse hybrid
TargetHER2/neu, CD3
Clinical data
Trade namesRexomun
ATC code
  • none
Identifiers
CAS Number
ChemSpider
  • none
UNII
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Ertumaxomab (trade name Rexomun) is a rat-murine hybrid monoclonal antibody designed to treat some types of cancer.

It is a trifunctional antibody which works by linking T-lymphocytes and macrophages to the cancer cells.[1]

Phase II clinical trial evaluating the treatment of breast cancer was terminated due to change in Fresenius' development plans.[2] (So they could concentrate on their other product catumaxomab (trade name Removab).[3]: 35 )

References

  1. ^ Fresenius
  2. ^ ClinicalTrials.gov: Phase II Study With the Trifunctional Antibody Ertumaxomab to Treat Metastatic Breast Cancer After Progression on Trastuzumab Therapy
  3. ^ "2009 Consolidated Financial Statements and Management Report of Fresenius SE" (PDF). Archived from the original (PDF) on 2016-03-31. Retrieved 2016-03-20.



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