|West end||Lisbon, Portugal|
|East end||Silopi, Turkey|
European route E 90 is an A-Class West–East European route, extending from Lisbon in Portugal in the west to the Turkish–Iraqi border in the east.
The E 90 routes through five European countries, and includes four sea-crossings: Barcelona, Spain - Mazara del Vallo, Italy; Messina, Italy to Reggio Calabria, Italy; Brindisi, Italy, to Igoumenitsa, Greece, and Eceabat, Turkey, to Çanakkale, Turkey.
The Greek portion of E90 is known as Egnatia Odos, after the road built on top of a pre-Roman trail that spanned from the Adriatic to the Aegean, Via Egnatia. It was later extended to Byzantium (Constantinople) to the east and Rome to the west. The name Egnatia comes from the Roman proconsul, Gnaius Egnatius, who built the original road. In its design phase, Egnatia Odos was planned to have 1650 bridges, 43 river crossings, 11 railway crosses, and 50 interchanges with existing roads.