FUT2
Identifiers
Aliases	FUT2, B12QTL1, SE, SEC2, Se2, sej, fucosyltransferase 2
External IDs	OMIM: 182100 MGI: 109374 HomoloGene: 10325 GeneCards: FUT2
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.33 Start 48,695,971 bp[1] End 48,705,951 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 B3|7 29.41 cM Start 45,298,015 bp[2] End 45,315,818 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in minor salivary glands pancreatic ductal cell duodenum oral cavity rectum palpebral conjunctiva jejunal mucosa gallbladder cervix epithelium gums Top expressed in lip left colon epithelium of stomach seminal vesicula duodenum esophagus skin of back uterus ileum epidermis More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity galactoside 2-alpha-L-fucosyltransferase activity glycosyltransferase activity fucosyltransferase activity Cellular component integral component of membrane Golgi cisterna membrane Golgi apparatus extracellular exosome membrane Biological process protein glycosylation L-fucose catabolic process fucosylation carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2524 14344 Ensembl ENSG00000176920 ENSMUSG00000055978 UniProt Q10981 Q9JL27 RefSeq (mRNA) NM_001097638 NM_000511 NM_001271993 NM_018876 RefSeq (protein) NP_000502 NP_001091107 NP_001258922 NP_061364 Location (UCSC) Chr 19: 48.7 – 48.71 Mb Chr 7: 45.3 – 45.32 Mb PubMed search [3] [4]
Wikidata
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Galactoside 2-alpha-L-fucosyltransferase 2 is an enzyme that in humans is encoded by the FUT2 gene.^[5][6] It affects the secretor status of ABO antigens.^[7]

Approximately 20% of Caucasians are non-secretors due to the G428A (rs601338) and C571T (rs492602?) nonsense mutations in FUT2 and therefore have strong although not absolute protection from the norovirus GII.4.^{[citation needed]}