Fibrin monomers are monomers of fibrin which are formed by the cleavage of fibrinogen by thrombin.[1] Levels of fibrin monomers can be measured using blood tests and can serve as a marker of in vivo fibrinogenesis and coagulation activation.[1][2][3] They may be useful in the evaluation hypercoagulability.[1]

Levels of fibrin monomers may be increased with pregnancy[1] and by estrogen-containing combined birth control pills.[2]

References

  1. ^ a b c d Refaai MA, Riley P, Mardovina T, Bell PD (November 2018). "The Clinical Significance of Fibrin Monomers". Thromb Haemost. 118 (11): 1856–1866. doi:10.1055/s-0038-1673684. PMID 30312978.
  2. ^ a b Douxfils J, Morimont L, Bouvy C (November 2020). "Oral Contraceptives and Venous Thromboembolism: Focus on Testing that May Enable Prediction and Assessment of the Risk". Semin Thromb Hemost. 46 (8): 872–886. doi:10.1055/s-0040-1714140. PMID 33080636. S2CID 224821517.
  3. ^ Farris M, Bastianelli C, Rosato E, Brosens I, Benagiano G (October 2017). "Pharmacodynamics of combined estrogen-progestin oral contraceptives: 2. effects on hemostasis". Expert Rev Clin Pharmacol. 10 (10): 1129–1144. doi:10.1080/17512433.2017.1356718. PMID 28712325. S2CID 205931204.



Categories