Ball-and-stick model of the flephedrone molecule
Clinical data
Routes of
Oral, insufflation, vaporized
Legal status
Legal status
  • 1-(4-Fluorophenyl)-2-(methylamino)propan-1-one
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.231.256 Edit this at Wikidata
Chemical and physical data
Molar mass181.210 g·mol−1
3D model (JSmol)
ChiralityRacemic mixture
  • CNC(C)C(=O)c(cc1)ccc1F
  • InChI=1S/C10H12FNO/c1-7(12-2)10(13)8-3-5-9(11)6-4-8/h3-7,12H,1-2H3 checkY
 ☒NcheckY (what is this?)  (verify)

Flephedrone, also known as 4-fluoromethcathinone (4-FMC), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug starting in 2008.[2]


Flephedrone has only a short history of human use and its toxicity is not well established.[3]


Flephedrone has been illegal in Denmark since December 2008.[citation needed]

Flephedrone has been illegal in the UK since April 2010. Flephedrone has been illegal in the Lithuania since April 2010. Flephedrone is illegal in Brazil since 2017 as an analogue or derivative of cathinone. Flephedrone is most likely illegal in Australia as an analogue or derivative of cathinone.

Flephedrone has been illegal in Poland since April 2010.[4]

Flephedrone has been classed as a narcotic in Sweden since October 2010.[5]

In the United States, flephedrone is temporarily listed as a Schedule I controlled substance.[1] It is permanently listed as a Schedule I controlled substance in Florida,[6] Georgia, and Pennsylvania.[7]

As of October 2015 4-FMC is a controlled substance in China.[8]

See also


  1. ^ a b "Schedules of Controlled Substances: Temporary Placement of 10 Synthetic Cathinones Into Schedule I". Federal Register. The Daily Journal of the United States Government.
  2. ^ Archer RP (March 2009). "Fluoromethcathinone, a new substance of abuse". Forensic Science International. 185 (1–3): 10–20. doi:10.1016/j.forsciint.2008.11.013. PMID 19195800.
  3. ^ Thornton SL, Gerona RR, Tomaszewski CA (September 2012). "Psychosis from a bath salt product containing flephedrone and MDPV with serum, urine, and product quantification". Journal of Medical Toxicology. 8 (3): 310–3. doi:10.1007/s13181-012-0232-4. PMC 3550171. PMID 22528592.
  4. ^ "Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. Retrieved 17 June 2011.
  5. ^ "Läkemedelsverkets författningssamling" [The Swedish Medicines Agency's constitutional collection] (PDF). Medical Products Agency (Sweden), Läkemedelsverkets författningssamling (in Swedish).
  6. ^ "Notice of Emergency Rule" (PDF). Department of Business and Professional Regulation. State of Florida.
  7. ^ "Sensate Bill 1006". The General Assembly of Pennsylvania. 2011.
  8. ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015.