Fourphit
Names
Preferred IUPAC name
4-Isothiocyanato-1-(1-phenylcyclohexyl)piperidine
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2
    Key: QAHYIAVTWZVTMY-UHFFFAOYSA-N
  • InChI=1/C18H24N2S/c21-15-19-17-9-13-20(14-10-17)18(11-5-2-6-12-18)16-7-3-1-4-8-16/h1,3-4,7-8,17H,2,5-6,9-14H2
    Key: QAHYIAVTWZVTMY-UHFFFAOYAR
  • c1ccc(cc1)C2(CCCCC2)N3CCC(CC3)N=C=S
Properties
C18H24N2S
Molar mass 300.46 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Fourphit (4-isothiocyanato-1-[1-phenylcyclohexyl]piperidine) is a covalent binding NMDA antagonist, dopaminergic and sigma receptor agonist.[1]

See also

References

  1. ^ Schweri, M. M.; De Costa, B. R.; Rice, K. C. (1998). "Fourphit, an acylating phencyclidine derivative, attenuates cocaine-induced hyperactivity in rats". Pharmacology Biochemistry and Behavior. 60 (3): 615–23. doi:10.1016/s0091-3057(98)00040-9. PMID 9678644. S2CID 1151532.


Categories