GABRP
Identifiers
Aliases	GABRP, gamma-aminobutyric acid type A receptor pi subunit, gamma-aminobutyric acid type A receptor subunit pi
External IDs	OMIM: 602729 MGI: 2387597 HomoloGene: 22798 GeneCards: GABRP
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q35.1 Start 170,763,350 bp[1] End 170,814,047 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 A4 Start 33,500,781 bp[2] End 33,528,959 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva endometrium lactiferous duct amniotic fluid bronchial epithelial cell pancreatic ductal cell minor salivary gland cavity of mouth skin of abdomen vagina Top expressed in trachea right lung lobe olfactory epithelium abdominal wall secondary oocyte seminal vesicula lip skin of abdomen cervix right ventricle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function extracellular ligand-gated ion channel activity chloride channel activity GABA-A receptor activity ion channel activity transmembrane signaling receptor activity Cellular component integral component of membrane cell junction postsynaptic membrane plasma membrane synapse membrane chloride channel complex GABA-A receptor complex integral component of plasma membrane neuron projection Biological process ion transmembrane transport chloride transport ion transport signal transduction chloride transmembrane transport chemical synaptic transmission regulation of membrane potential nervous system process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2568 216643 Ensembl ENSG00000094755 ENSMUSG00000020159 UniProt O00591 Q8QZW7 RefSeq (mRNA) NM_001291985 NM_014211 NM_146017 RefSeq (protein) NP_001278914 NP_055026 NP_666129 Location (UCSC) Chr 5: 170.76 – 170.81 Mb Chr 11: 33.5 – 33.53 Mb PubMed search [3] [4]
Wikidata
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Gamma-aminobutyric acid receptor subunit pi is a protein that in humans is encoded by the GABRP gene.^[5][6]

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.^[6]