GDF1
Identifiers
Aliases	GDF1, DORV, DTGA3, RAI, growth differentiation factor 1, CHTD6, UOG1, LASS1, CERS1, LAG1
External IDs	OMIM: 602880 MGI: 95683 HomoloGene: 105644 GeneCards: GDF1
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.11 Start 18,868,545 bp[1] End 18,896,158 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 B3.3 Start 70,782,467 bp[2] End 70,784,237 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve superior frontal gyrus ganglionic eminence skeletal muscle tissue prefrontal cortex sensory nervous system sensory organ face Brodmann area 9 gastrocnemius muscle Top expressed in superior frontal gyrus adrenal gland notochord cerebellar cortex urinary bladder yolk sac white adipose tissue ganglionic eminence limb islet of Langerhans More reference expression data BioGPS n/a
Gene ontology Molecular function transforming growth factor beta receptor binding cytokine activity growth factor activity Cellular component extracellular region extracellular space Biological process regulation of apoptotic process positive regulation of pathway-restricted SMAD protein phosphorylation regulation of MAPK cascade SMAD protein signal transduction cell development BMP signaling pathway regulation of signaling receptor activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2657 14559 Ensembl ENSG00000130283 ENSMUSG00000109523 UniProt P27539 P20863 RefSeq (mRNA) NM_001492 NM_001387438 NM_001163282 NM_008107 RefSeq (protein) NP_001483 NP_001156754 NP_032133 Location (UCSC) Chr 19: 18.87 – 18.9 Mb Chr 8: 70.78 – 70.78 Mb PubMed search [3] [4]
Wikidata
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Growth differentiation factor 1 (GDF1) is a protein that in humans is encoded by the GDF1 gene.^[5]

GDF1 belongs to the transforming growth factor beta superfamily that has a role in left-right patterning and mesoderm induction during embryonic development.^[6] It is found in the brain, spinal cord and peripheral nerves of embryos.^[5][6]