ADGRD2
Identifiers
AliasesADGRD2, PGR24, GPR144, adhesion G protein-coupled receptor D2
External IDsHomoloGene: 130029 GeneCards: ADGRD2
Orthologs
SpeciesHumanMouse
Entrez

347088

n/a

Ensembl

ENSG00000180264

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UniProt

n
a

n/a

RefSeq (mRNA)

NM_001161808
NM_182611
NM_001395425

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 9: 124.45 – 124.48 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Probable G-protein coupled receptor 144 is a protein that in humans is encoded by the GPR144 gene.[3][4] This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterised by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000180264 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Entrez Gene: GPR144 G protein-coupled receptor 144".
  4. ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. S2CID 7449692.
  5. ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 978-1-4419-7912-4.
  6. ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914.

Further reading

Categories