GPR45
Identifiers
Aliases	GPR45, PSP24, PSP24(ALPHA), PSP24A, G protein-coupled receptor 45
External IDs	OMIM: 604838 MGI: 2135882 HomoloGene: 5228 GeneCards: GPR45
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q12.1 Start 105,241,743 bp[1] End 105,243,467 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 B Start 42,992,032 bp[2] End 43,074,616 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Brodmann area 9 cingulate gyrus hypothalamus nucleus accumbens amygdala embryo caudate nucleus putamen substantia nigra Top expressed in ganglionic eminence arcuate nucleus paraventricular nucleus of hypothalamus dorsomedial hypothalamic nucleus superior frontal gyrus ventral tegmental area dorsal tegmental nucleus superior colliculus facial motor nucleus nucleus accumbens More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process signal transduction G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 11250 93690 Ensembl ENSG00000135973 ENSMUSG00000041907 UniProt Q9Y5Y3 Q9EQQ4 RefSeq (mRNA) NM_007227 NM_053107 RefSeq (protein) NP_009158 NP_444337 Location (UCSC) Chr 2: 105.24 – 105.24 Mb Chr 1: 42.99 – 43.07 Mb PubMed search [3] [4]
Wikidata
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Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.^[5][6]

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.^[6]