LGALS7
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UW5, 2GAL, 4GAL, 1BKZ, 4UW4, 3ZXE, 3GAL, 3ZXF, 4UW6, 4XBQ, 5GAL, 4UW3, 5H9S, 4Y26, 5H9Q
Identifiers
Aliases	LGALS7, GAL7, LGALS7A, galectin 7
External IDs	OMIM: 600615 MGI: 1316742 HomoloGene: 100509 GeneCards: LGALS7
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.2 Start 38,770,968 bp[1] End 38,773,517 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 B1 Start 28,563,278 bp[2] End 28,565,709 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen vagina minor salivary gland right lung spleen gastric mucosa thymus fundus gastrocnemius muscle left lobe of thyroid gland Top expressed in lip esophagus superior surface of tongue skin of abdomen skin of back belly cord epidermis hair follicle condyle fossa More reference expression data BioGPS n/a
Gene ontology Molecular function carbohydrate binding Cellular component cytoplasm extracellular region extracellular exosome nucleus extracellular space Biological process heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules apoptotic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3963 16858 Ensembl ENSG00000283082 ENSG00000205076 ENSMUSG00000053522 UniProt P47929 O54974 RefSeq (mRNA) NM_002307 NM_008496 RefSeq (protein) NP_002298 NP_001035972 n/a Location (UCSC) Chr 19: 38.77 – 38.77 Mb Chr 7: 28.56 – 28.57 Mb PubMed search [3] [4]
Wikidata
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Galectin-7 is a protein that in humans is encoded by the LGALS7 gene.^[5][6][7]

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the suprabasal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell–cell and/or cell–matrix interactions necessary for normal growth control.^[7]