George Kelly may refer to:

Entertainment

• George Kelly (musician) (1915–1998), American jazz tenor saxophonist, vocalist, arranger and bandleader
• George Kelly (playwright) (1887–1974), American dramatist
• George "Fowokan" Kelly (born 1943), Jamaica-born British visual artist
• George M. Kelly (born 1952), New York sculptor who created a George Washington bronze for the Millennium Gate museum in Atlanta

Sports

• George A. Kelly (1883–1969), American football coach in the United States
• George Kelly (baseball) (1895–1984), American first baseman; played 1915–1932
• George Kelly (boxer), Irish boxer who competed at the 1928 Summer Olympics in Amsterdam
• George Kelly (footballer) (1933–1998), footballer who played for Cardiff City, Stockport County and Stoke City

Other

• George Kelly (Jacobite) (c.1680–1762), Irish agent of Charles Edward Stuart
• George Kelly (psychologist) (1905–1967), American personality theorist and professor at Ohio State University
• George B. Kelly (1900–1971), Democratic member of the United States House of Representatives from New York
• George Kelly (British Army officer) (1880–1938)
• George E. M. Kelly (1878–1911), American Army 2nd lieutenant; namesake of San Antonio's Kelly Field Annex
• George Kelly (billiards player), American champion pool competitor of the 1920s and 30s; nephew of George Kelly
• Mike Kelly (Pennsylvania politician) (George Joseph Kelly Jr., born 1948), member of the U.S. House of Representatives