George Mackay or Mckay may refer to:

Arts and entertainment

• George McKay (actor) (1884–1945), Russian-American actor
• George Frederick McKay (1899–1970), American composer
• George MacKay (actor) (born 1992), English actor

Law and politics

• George Mackay of Skibo (c. 1715–1782), Scottish soldier and MP for Sutherland
• George R. McKay (1817–1890), American politician in Michigan
• George McKay (Australian politician) (1819–1898), New South Wales colonial politician
• George Prevost McKay (1840–1924), Canadian businessman and political figure in Ontario
• George Mackay (Australian politician) (1872–1961), Speaker of the Australian House of Representatives

Sports

• George Mackay (cricketer) (1860–1948), Australian cricketer
• George MacKay (rower) (1900–1972), Canadian rower
• George McKay (rugby union) (fl. 1920–1922), Australian rugby union player
• George Mackay (rugby union) (1906–1981), Australian rugby union player

Others

• George Mackay, 3rd Lord Reay (1678–1748), Scottish noble
• George Mackay, 5th Lord Reay (1735–1768), Scottish noble
• George Leslie Mackay (1844–1901), Canadian missionary
• George Mackay (surgeon) (1861–1949), British ophthalmic surgeon
• George William Mackay (1882–1969), Canadian missionary in Taiwan
• George Chisholm MacKay (1898–1973), Canadian World War I pilot