Cardano partially invented and described several mechanical devices including the combination lock, the gimbal consisting of three concentric rings allowing a supported compass or gyroscope to rotate freely, and the Cardan shaft with universal joints, which allows the transmission of rotary motion at various angles and is used in vehicles to this day. He made significant contributions to hypocycloids, published in De proportionibus, in 1570. The generating circles of these hypocycloids were later named Cardano circles or cardanic circles and were used for the construction of the first high-speed printing presses.
Cardano was born on the 24th of September, 1501 in Pavia, Lombardy, the illegitimate child of Fazio Cardano, a mathematically gifted jurist, lawyer, and close personal friend of Leonardo da Vinci. In his autobiography, Cardano wrote that his mother, Chiara Micheri, had taken "various abortive medicines" to terminate the pregnancy; he was "taken by violent means from my mother; I was almost dead." She was in labour for three days. Shortly before his birth, his mother had to move from Milan to Pavia to escape the Plague; her three other children died from the disease.
After a depressing childhood, with frequent illnesses, including impotence, and the rough upbringing by his overbearing father, in 1520, Cardano entered the University of Pavia against the wish of his father, who wanted his son to undertake studies of law, but Girolamo felt more attracted to philosophy and science. During the Italian War of 1521–1526, however, the authorities in Pavia were forced to close the university in 1524. Cardano resumed his studies at the University of Padua, where he graduated with a doctorate in medicine in 1525. His eccentric and confrontational style did not earn him many friends and he had a difficult time finding work after his studies had ended. In 1525, Cardano repeatedly applied to the College of Physicians in Milan, but was not admitted owing to his combative reputation and illegitimate birth. However, he was consulted by many members of the College of Physicians, because of his irrefutable intelligence.
Early career as a physician
Cardano wanted to practice medicine in a large, rich city like Milan, but he was denied a licence to practice, so he settled for the town of Saccolongo, where he practised without a license. There, he married Lucia Banderini in 1531. Before her death in 1546, they had three children, Giovanni Battista (1534), Chiara (1537) and Aldo Urbano (1543). Cardano later wrote that those were the happiest days of his life.
With the help of a few noblemen, Cardano obtained a teaching position in mathematics in Milan. Having finally received his medical licence, he practised mathematics and medicine simultaneously, treating a few influential patients in the process. Because of this, he became one of the most sought-after doctors in Milan. In fact, by 1536, he was able to quit his teaching position, although he was still interested in mathematics. His notability in the medical field was such that the aristocracy tried to lure him out of Milan. Cardano later wrote that he turned down offers from the kings of Denmark and France, and the Queen of Scotland.
Cardano was the first mathematician to make systematic use of negative numbers. He published with attribution the solution of Scipione del Ferro to the cubic equation and the solution of Cardano's student Lodovico Ferrari to the quartic equation in his 1545 book Ars Magna, an influential work on algebra. The solution to one particular case of the cubic equation  (in modern notation) had been communicated to him in 1539 by Niccolò Fontana Tartaglia (who later claimed that Cardano had sworn not to reveal it, and engaged Cardano in a decade-long dispute) in the form of a poem, but del Ferro's solution predated Tartaglia's. In his exposition, he acknowledged the existence of what are now called imaginary numbers, although he did not understand their properties, described for the first time by his Italian contemporary Rafael Bombelli. In Opus novum de proportionibus he introduced the binomial coefficients and the binomial theorem.
Cardano was notoriously short of money and kept himself solvent by being an accomplished gambler and chess player. His book about games of chance, Liber de ludo aleae ("Book on Games of Chance"), written around 1564, but not published until 1663, contains the first systematic treatment of probability, as well as a section on effective cheating methods. He used the game of throwing dice to understand the basic concepts of probability. He demonstrated the efficacy of defining odds as the ratio of favourable to unfavourable outcomes (which implies that the probability of an event is given by the ratio of favourable outcomes to the total number of possible outcomes). He was also aware of the multiplication rule for independent events but was not certain about what values should be multiplied.
This section needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed. (September 2017) (Learn how and when to remove this template message)
"Oneiron" ("Dream"), reverse of the medallion of Cardano by Leone Leoni, 1550-51.
Cardano's work with hypocycloids led him to Cardan's Movement or Cardan Gear mechanism, in which a pair of gears with the smaller being one-half the size of the larger gear is used converting rotational motion to linear motion with greater efficiency and precision than a Scotch yoke, for example. He is also credited with the invention of the Cardan suspension or gimbal.
Cardano made several contributions to hydrodynamics and held that perpetual motion is impossible, except in celestial bodies. He published two encyclopedias of natural science which contain a wide variety of inventions, facts, and occult superstitions. He also introduced the Cardan grille, a cryptographic writing tool, in 1550.
Significantly, in the history of education of the deaf, he said that deaf people were capable of using their minds, argued for the importance of teaching them, and was one of the first to state that deaf people could learn to read and write without learning how to speak first. He was familiar with a report by Rudolph Agricola about a deaf mute who had learned to write.
Cardano's medical writings included: a commentary on Mundinus' anatomy and of Galen's medicine, alog with the treaties Delle cause, dei segni e dei luoghi delle malattie, Picciola terapeutica, Degli abusi dei medici and Delle orine, libro quattro.
Cardano has been credited with the invention of the so-called Cardano's Rings, also called Chinese Rings, but it is very probable that they predate Cardano. The universal joint, sometimes called Cardan joint, was not described by Cardano.
The title of a work of Cardano's, published in 1552, De Subtilitate (corresponding to what would now be called transcendental philosophy), would lead us to expect, in the chapter on minerals, many far fetched theories characteristic of that age; but when treating of petrified shells, he decided that they clearly indicated the former sojourn of the sea upon the mountains.
Later years and death
In 1553 Cardono traveled to Scotland to treat the Archbishop of St Andrews who suffered of a disease that had left him speechless and was thought incurable The treatment was a success and the diplomat Thomas Randolph recorded that "merry tales" about Cardano's methods were still current in Edinburgh in 1562. Cardano wrote that the Archbishop had been short of breath for ten years, and after the cure was effected by his assistant, he was paid 1,400 gold crowns.
Medallion portrait of Cardano aged 49 by Leone Leoni (1509-1590)
Two of Cardano's children — Giovanni Battista and Aldo Urbano — came to ignoble ends. Giovanni Battista, Cardano's eldest and favorite son was arrested in 1560 for having poisoned his wife, after he had discovered that their three children were not his. Giovanni was put to trial and, when Cardano could not pay the restitution demanded by the victim's family, was sentenced to death and beheaded. Cardano's other son Aldo Urbano was a gambler, who stole money from his father, and so Gerolamo disinherited him in 1569.
Cardano moved from Pavia to Bologna, in part because he believed that the decision to execute his son was influenced by Gerolamo's battles with the academic establishment in Pavia, and his colleagues' jealousy at his scientific achievements, and also because he was beset with allegations of sexual impropriety with his students. He obtained a position as professor of medicine at the University of Bologna.
Cardano was arrested by the Inquisition in 1570 after an accusation of heresy by the Inquisitor of Como, who targeted Cardano's De rerum varietate (1557). The inquisitors complained about Cardano's writings on astrology, especially his claim that self-harming religiously motivated actions of martyrs and heretics were caused by the stars. In his 1543 book De Supplemento Almanach, a commentary on the astrological work Tetrabiblos by Ptolemy, Cardano had also published a horoscope of Jesus. Cardano was imprisoned for several months and lost his professorship in Bologna. He abjured and was freed, probably with help from powerful churchmen in Rome. All his non-medical works were prohibited and placed on the Index.
He moved to Rome, where he received a lifetime annuity from Pope Gregory XIII (after first having been rejected by Pope Pius V, who died in 1572) and finished his autobiography. He was accepted in the Royal College of Physicians, and as well as practising medicine he continued his philosophical studies until his death in 1576.
References in literature and culture
The seventeenth-century English physician and philosopher Sir Thomas Browne possessed the ten volumes of the Leyden 1663 edition of the complete works of Cardan in his library.
Browne critically viewed Cardan as:
"that famous Physician of Milan, a great Enquirer of Truth, but too greedy a Receiver of it. He hath left many excellent Discourses, Medical, Natural, and Astrological; the most suspicious are those two he wrote by admonition in a dream, that is De Subtilitate & Varietate Rerum. Assuredly this learned man hath taken many things upon trust, and although examined some, hath let slip many others. He is of singular use unto a prudent Reader; but unto him that only desireth Hoties,[a] or to replenish his head with varieties; like many others before related, either in the Original or confirmation, he may become no small occasion of Error."
Cardan believ'd great states depend
Upon the tip o'th' Bear's tail's end;
That, as she wisk'd it t'wards the Sun,
Strew'd mighty empires up and down;
Which others say must needs be false,
Because your true bears have no tails.
Alessandro Manzoni's novel I Promessi Sposi portrays a pedantic scholar of the obsolete, Don Ferrante, as a great admirer of Cardano. Significantly, he values him only for his superstitious and astrological writings; his scientific writings are dismissed because they contradict Aristotle, but excused on the ground that the author of the astrological works deserves to be listened to even when he is wrong.
English novelist E. M. Forster's Abinger Harvest, a 1936 volume of essays, authorial reviews and a play, provides a sympathetic treatment of Cardano in the section titled 'The Past'. Forster believes Cardano was so absorbed in "self-analysis that he often forgot to repent of his bad temper, his stupidity, his licentiousness, and love of revenge" (212).
De malo recentiorum medicorum medendi usu libellus, Hieronymus Scotus, Venice, 1536 (on medicine).
Practica arithmetice et mensurandi singularis (on mathematics), Io. Antoninus Castellioneus/Bernadino Caluscho, Milan, 1539.
De Consolatione, Libri tres, Hieronymus Scotus, Venice, 1542.
^Patty, Peter Fletcher, Hughes Hoyle, C. Wayne (1991). Foundations of Discrete Mathematics (International student ed.). Boston: PWS-KENT Pub. Co. p. 207. ISBN0-534-92373-9. Cardano was a physician, astrologer, and mathematician.... [He] supported his wife and three children by gambling and casting horoscopes.
^Burton, David. The History of Mathematics: An Introduction (7th (2010) ed.). New York: McGraw-Hill.
^V.J. Katz, A History of Mathematics: An Introduction, 3rd edn. (Boston: Pearson Education, 2009).
^In Chapter 20 of Liber de Ludo Aleae he describes a personal experience from 1526 and then adds that "thirty-eight years have passed" [elapsis iam annis triginta octo]. This sentence is written by Cardano around 1564, age 63.
Giglioni, Guido, "'Bolognan boys are beautiful, tasteful and mostly fine musicians': Cardano on male same-sex love and music", in: Kenneth Borris & George Rousseau (curr.), The sciences of homosexuality in early modern Europe, Routledge, London 2007, pp. 201–220.
Morley, Henry, The life of Girolamo Cardano, of Milan, Physician 2 vols. Chapman & Hall, London 1854.
Ore, Øystein, Cardano, the Gambling Scholar. Princeton, 1953.
Rutkin, H. Darrel, "Astrological conditioning of same-sexual relations in Girolamo Cardano's theoretical treatises and celebrity genitures", in: Kenneth Borris & George Rousseau (curr.), The sciences of homosexuality in early modern Europe, Routledge, London 2007, pp. 183–200.
Georgio Vivi (ed.), Cardani Mediolanensis Philosophi ac Medici Celeberrimi Bibliographia, Tertia Editio (Author, 'Cosmopoli', 2018), View free at Scribd. A very compendious bibliography of works referring to Cardano.