Gianfranco is a compound Italian given name, consisting of Gian- and Franco. Gian- comes from Giovanni and is used in compound names. It is closest to John or French Jean. Gianni means "God is gracious" and Franco means "Free man" or "Frenchman", a contracted form of Francesco.

Notable people with the given name include:

• Gianfranco Brancatelli (born 1950), Italian racing driver
• Gianfranco Dettori (born 1951), Italian jockey, father of Frankie Dettori
• Gianfranco Ferré (1944–2007), Italian fashion designer
• Gianfranco Fini (born 1952), Italian politician
• Gianfranco Parolini (1925–2018), Italian film director
• Gianfranco Rotondi (born 1960), Italian politician
• Gianfranco Seramondi (born 1958), Swiss footballer
• Gianfranco Zola (born 1966), Italian footballer