Gianluca is an Italian masculine given name. Its English translation is "John Luke" and it is often a shorter form of "Giovanni Luca".

• Gianluca Alfenoni (born 1996), Argentine footballer
• Gianluca Arrighi (born 1972), Italian writer
• Gianluca Attanasio (born 1979), Italian singer-songwriter, composer, and film director
• Gianluca Atzori (born 1971), Italian footballer and manager
• Gianluca Bacchiocchi (born 1987), Italian footballer
• Gianluca Barattolo (born 1978), Italian rowing coxswain
• Gianluca Barba (born 1995), Italian footballer
• Gianluca Barilari (born 1964), Swiss basketball coach
• Gianluca Basile (born 1975), Italian basketball player
• Gianluca Berti (born 1967), Italian footballer
• Gianluca Bezzina (born 1989), Maltese singer and doctor, also known by the mononym Gianluca
• Gianluca Bocchi (born 1954), Italian philosopher
• Gianluca Bollini (born 1980), Sammarinese footballer
• Gianluca Bortolami (born 1968), Italian road cyclist
• Gianluca Brambilla (born 1987), Italian road bicycle racer
• Gianluca Branco (born 1970), Italian boxer
• Gianluca Buonanno (1966–2016), Italian politician
• Gianluca Busato (born 1969), Italian entrepreneur, engineer, activist, and politician
• Gianluca Busio (born 2002), American soccer player
• Gianluca Caprari (born 1993), Italian footballer
• Gianluca Carpani (born 1993), Italian footballer
• Gianluca Cascioli (born 1979), Italian pianist, conductor, and composer
• Gianluca Castellini (fl. 15th-century), Italian Roman Catholic prelate and bishop
• Gianluca Catalano (born 2000), Canadian soccer player
• Gianluca Cherubini (born 1974), Italian footballer
• Gianluca Cologna (born 1990), Swiss cross-country skier
• Gianluca Comotto (born 1978), Italian footballer
• Gianluca Conte (born 1972), Italian footballer, manager, and analyzer
• Gianluca Costantini (born 1971), Italian cartoonist, artist, and activist
• Gianluca Crisafi (born 1974), Italian voice actor
• Gianluca Cuomo (born 1993), American soccer player
• Gianluca Curci (born 1985), Italian footballer
• Gianluca D'Angelo (born 1991), Swiss footballer
• Gianluca De Angelis (born 1967), Italian footballer
• Gianluca De Angelis (born 1981), Italian footballer
• Gianluca de Lorenzi (born 1972), Italian auto racing driver and team owner
• Gianluca De Ponti (born 1952), Italian footballer
• Gianluca Di Chiara (born 1993), Italian footballer
• Gianluca Di Giulio (born 1972), Italian footballer
• Gianluca Faliva (born 1973), Italian rugby player
• Gianluca Falsini (born 1975) Italian footballer and manager
• Gianluca Farina (born 1962), Italian rower
• Gianluca Ferrari (born 1997), Argentine footballer
• Gianluca Festa (born 1959), Italian footballer
• Gianluca Festa (born 1974), Italian politician.
• Gianluca Firmo (Born 1973), Italian singer and musician
• Gianluca Floris (born 1964), Italian writer and belcanto singer
• Gianluca Forcolin (born 1968), Italian politician
• Gianluca Frabotta (born 1999), Italian footballer
• Gianluca Francesconi (born 1971), Italian footballer
• Gianluca Franciosi (born 1991), Italian footballer
• Gianluca Frontino (born 1989), Swiss footballer
• Gianluca Freddi (born 1989), Italian footballer
• Gianluca Gaetano (born 2000), Italian footballer
• Gianluca Galasso (born 1984), Italian footballer
• Gianluca Galimberti (born 1968), Italian professor and politician
• Gianluca Gaudenzi (born 1965), Italian footballer and coach
• Gianluca Gaudino (born 1996), German footballer
• Gianluca Ginoble (born 1995), Italian baritone of the boyband Il Volo
• Gianluca Giovannini (born 1983), Italian footballer
• Gianluca Gorini (born 1970), Italian racing cyclist
• Gianluca Gracco (born 1990), Italian footballer
• Gianluca Grassadonia (born 1972), Italian footballer and coach
• Gianluca Grava (born 1977), Italian footballer
• Gianluca Grignani (born 1972), Italian singer
• Gianluca Guidi (born 1968), Italian rugby player and coach
• Gianluca Havern (born 1988), English footballer
• Gianluca Hossmann (born 1991), Swiss footballer
• Gianluca Iacono (born 1970), Italian voice actor
• Gian-Luca Itter (born 1999), German footballer
• Gianluca Korte (born 1990), German footballer
• Gianluca Lapadula (born 1990), Italian footballer
• Gianluca Litteri (born 1988), Italian footballer
• Gianluca Luisi (born 1970), Italian pianist
• Gianluca Luppi (born 1966), Italian footballer and coach
• Gianluca Mager (born 1994), Italian tennis player
• Gianluca Maggiore (born 1985), Italian racing cyclist
• Gianluca Maglia (born 1988), Italian swimmer
• Gianluca Mancini (born 1996), Italian footballer
• Gianluca Mancuso (born 1998), Argentine footballer
• Gianluca Marchetti (born 1993), Italian basketball player
• Gianluca Maria (born 1992), Curaçaoan footballer
• Gianluca Marzullo (born 1991), Italian footballer
• Gianluca Masi (born 1972), Italian astrophysicist and astronomer
• Gianluca Musacci (born 1987), Italian footballer
• Gianluca Nani (born 1962), Italian football director
• Gianluca Naso (born 1987), Italian tennis player
• Gianluca Nicco (born 1988), Italian footballer
• Gianluca Nijholt (born 1990), Dutch professional footballer
• Gianluca Pagliuca (born 1966), Italian footballer and coach
• Gianluca Pandeynuwu (born 1997), Indonesian footballer
• Gianluca Paparesta (born 1969), Italian football referee
• Gianluca Pegolo (born 1981), Italian footballer
• Gianluca Pessotto (born 1970), Italian footballer
• Gianluca Petrachi (born 1969), Italian footballer
• Gianluca Petrella (born 1975), Italian jazz trombonist
• Gianluca Pianegonda (born 1968), Italian racing cyclist
• Gianluca Piccoli (born 1997), Italian footballer
• Gianluca Pierobon (born 1967), Italian racing cyclist
• Gianluca Pollace (born 1995), Italian football player
• Gianluca Pozzi (born 1965), Italian tennis player
• Gianluca Prestianni (born 2006), Argentine footballer
• Gianluca Pugliese (born 1997), Argentine footballer
• Gianluca Ramazzotti (born 1970), Italian actor
• Gianluca Rinaldini (born 1959), Italian tennis player
• Gianluca Rocchi (born 1973), Italian football referee
• Gianluca Sampietro (born1993), Italian footballer
• Gianluca Sansone (born 1987), Italian footballer
• Gianluca Savoldi (born 1975), Italian footballer
• Gianluca Scamacca (born 1999), Italian footballer
• Gianluca Segarelli (born 1978), Italian footballer
• Gianluca Signorini (1960–2002), Italian footballer
• Gianluca Simeone (born 1998), Argentine footballer
• Gianluca Sironi (born 1974), Italian cyclist
• Gianluca Sordo (born 1969), Italian footballer
• Gianluca Spinelli (born 1966), Italian football goalkeeper coach
• Gianluca Susta (born 1956), Italian politician
• Gianluca Maria Tavarelli (born 1964), Italian film director and screenwriter
• Gianluca Temelin (born 1976), Italian footballer
• Gianluca Testa (born 1982), Italian actor and director
• Gianluca Tiberti (born 1967), Italian modern pentathlete
• Gianluca Tognon (born 1976), Italian food scientist, researcher, public health expert, and speaker
• Gianluca Toscano (born 1984), Italian footballer
• Gianluca Triuzzi (born 1978), Italian footballer
• Gianluca Turchetta (born 1991), Italian footballer
• Gianluca Valoti (born 1973), Italian road racing cyclist
• Gianluca Vialli (1964–2023), Italian footballer
• Gianluca Vivan (born 1983), Italian footballer
• Gianluca Vizziello (born 1980), Italian motorcycle racer
• Gianluca Zambrotta (born 1977), Italian footballer
• Gianluca Zanetti (born 1977), Italian footballer
• Gianluca Zavarise (born 1986), Canadian soccer player