Granuloma gluteale infantum
SpecialtyDermatology

Granuloma gluteale infantum is a cutaneous condition that appears in the anogenital region of infants as a complication of diaper dermatitis.[1] According to some, no granulomas are found.[2]

Signs and symptoms

In cases of primary irritant contact dermatitis, the lesions manifest clinically as numerous asymptomatic erythematous papules and nodules in the diaper area.[3]

Causes

Granuloma gluteale infantum is an uncommon dermatosis of infancy with an unknown etiology.[4] Contributing factors include prolonged use of fluorinated steroids,[5] and benzocaine,[6] diaper occlusion in incontinent adults and infants,[7] candidiasis,[8] and irritant contact dermatitis.[9]

Diagnosis

The histological picture shows an underlying hyperplastic epidermis and parakeratosis, accompanied by a non-specific perivascular dermal infiltrate made up of neutrophils, histiocytes, lymphocytes, plasma cells, and eosinophils.[10]

Treatment

In order to treat granuloma gluteale infantum, the diaper area needs to be kept dry and clean, and the irritant should be eliminated or lessened. It is recommended to use a barrier cream, such as zinc oxide.[11]

See also

References

  1. ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. ^ De Zeeuw R, Van Praag MC, Oranje AP (2000). "Granuloma gluteale infantum: a case report". Pediatr Dermatol. 17 (2): 141–3. doi:10.1046/j.1525-1470.2000.01734.x. hdl:1765/56610. PMID 10792807. S2CID 23487761.
  3. ^ Leung, Alexander K. C.; Leong, Kin Fon; Lam, Joseph M. (June 7, 2021). "Successful Treatment of Recalcitrant Granuloma Gluteale Infantum with Topical Tacrolimus 0.03% Ointment". Case Reports in Pediatrics. Hindawi Limited. 2021: 1–5. doi:10.1155/2021/9994067. ISSN 2090-6811. PMC 8203409. PMID 34194861.
  4. ^ Konya, Joseph; Gow, Elizabeth (1996). "Granuloma gluteale infantum". Australasian Journal of Dermatology. Wiley. 37 (1): 57–58. doi:10.1111/j.1440-0960.1996.tb00999.x. ISSN 0004-8380. S2CID 29839550.
  5. ^ Pons, S (1976). "[Granuloma gluteale infantum]". Medicina Cutanea Ibero-latino-americana. 4 (5): 359–364. PMID 1035390.
  6. ^ Dytoc, Marlene T.; Fiorillo, Loretta; Liao, Janice; Krol, Alfons L. (June 1, 2002). "Granuloma Gluteale Adultorum Associated with Use of Topical Benzocaine Preparations: Case Report and Literature Review". Journal of Cutaneous Medicine and Surgery: Incorporating Medical and Surgical Dermatology. SAGE Publications. 6 (3): 221–225. doi:10.1007/s10227-001-0042-9. ISSN 1203-4754. PMID 12001002.
  7. ^ Mostafa, Wedad Z.; Abahussein, Abdulaziz A.; Alzayer, Ahmed A. (1992). "Diaper Area Granuloma of Incontinence". The Journal of Dermatology. Wiley. 19 (5): 319–322. doi:10.1111/j.1346-8138.1992.tb03232.x. ISSN 0385-2407. PMID 1644958. S2CID 32495128.
  8. ^ De Zeeuw, Raymond; Van Praag, Marinus C. G.; Oranje, Arnold P. (2000). "Granuloma Gluteale Infantum: A Case Report". Pediatric Dermatology. Wiley. 17 (2): 141–143. doi:10.1046/j.1525-1470.2000.01734.x. hdl:1765/56610. ISSN 0736-8046. PMID 10792807. S2CID 23487761.
  9. ^ Walsh, S S; Robson, W J (June 1, 1988). "Granuloma gluteale infantum: an unusual complication of napkin dermatitis". Emergency Medicine Journal. BMJ. 5 (2): 113–115. doi:10.1136/emj.5.2.113. ISSN 1472-0205. PMC 1285498. PMID 3408529.
  10. ^ Al-Natour, SaharH; Al-Faraidy, NadyaA (2010). "A forgotten complication of diaper dermatitis: Granuloma gluteale infantum". Journal of Family and Community Medicine. Medknow. 17 (2): 107. doi:10.4103/1319-1683.71994. ISSN 2230-8229. PMC 3045094. PMID 21359035.
  11. ^ Ingersoll, Zachary; Garza-Chapa, Juana Irma; Pham, Ryan; Malouf, Peter; Susa, Joseph; Weis, Stephen (August 23, 2018). "Recurrent Granuloma Gluteale Infantum Secondary to Fecal Overflow Incontinence". Case Reports in Dermatology. S. Karger AG. 10 (2): 203–207. doi:10.1159/000492270. ISSN 1662-6567. PMC 6167654. PMID 30283312.

Further reading

External links

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