Great Eastern may refer to:

Transport

• SS Great Eastern, a steamship built by Isambard Kingdom Brunel in 1858, the largest ship of its era
• Great Eastern Railway, a defunct English railway company formed in 1862
  • First Great Eastern, a defunct train operating company on the Great Eastern Main Line
  • Great Eastern Main Line, a British railway line
• The Great Eastern, a bridge laying tank of World War II

Arts and entertainment

• The Great Eastern (radio show), that ran from 1994 to 1999 on CBC Radio One
• The Great Eastern (album), a 2000 album by the Scottish band The Delgados
• The Great Eastern (Rodman novel), a 2019 novel by Howard A. Rodman
• The Great Eastern (Embirikos novel), a 1990-1992 novel by Andreas Embirikos

Other uses

• Great Eastern Hotel (disambiguation)
• Great Eastern Life, an insurance company in Singapore and Malaysia