Great Western can refer to:

Locations

• Great Western, Victoria, a town in Victoria, Australia
• Great Western Divide, a long ridge in California's Sierra Nevada Mountains, USA
• Great Western Mountain, a mountain in central Sri Lanka
• Great Western Tiers, a collection of small mountain bluffs in Tasmania, Australia
• Great Western Woodlands, biodiverse area in South West Australia

Railways

• Great Western Railway, a UK railway company nationalised in 1948 and that has since lent its name to:
  • Great Western Main Line, a principal passenger and freight rail route
  • Great Western Railway (train operating company), traded as Great Western Trains until 1998, then First Great Western until 2015
  • Great Western Holdings, a company formed in 1994 to bid (successfully) for the Great Western franchise
  • Great Western was the name of several locomotives that were built for and run on the Great Western Railway, from different classes:
    • Iron Duke class
    • Rover class
    • 3031 Achilles or Dean Single class
    • 4073 Castle class
• Great Western Railway (Ontario), originally of Canada West
• Great Western Railway (Saskatchewan), a short line railway in Canada
• Chicago Great Western Railway, US
• Great Western Railroad (Illinois) (1853-1865), predecessor of the Wabash Railroad, US
• Great Western Railroad (Ohio), US
• Great Western Railway of Colorado, US
• Great Western railway station, near the Great Western Mountain, Sri Lanka

Businesses and organisations

• Great Western Air Ambulance Charity, helicopter ambulance trust in South West England
• Great Western Ambulance Service, a former NHS emergency services trust in South West England
• Great Western Arms Company, former firearms manufacturer in California, US
• Great Western Bank (disambiguation)
• Great Western Brewing Company, located in Saskatoon, Saskatchewan, Canada
• Great Western Business and Normal College, former college in Kansas, US
• Great Western Cities, partnership between Bristol, Cardiff and Newport, UK
• Great Western Combination, former football league in South Central England
• The Great Western Cotton Factory, former cotton mill in Bristol, UK
• Great Western Garment Co., former clothing company in Alberta, Canada
• Great Western Hospital, in Swindon, England
  • Great Western Hospitals NHS Foundation Trust runs the Great Western Hospital, Swindon
• Great Western Hotel (disambiguation), several hotels
• Great Western Lacrosse League, former sports conference in US
• Great Western Steam Laundry, former laundry in Glasgow, UK
• Great Western Mine, a coal mine in South Wales, UK
• Great Western Mine (Lake County, California), a mercury mine in California, USA
• Great Western Schoolhouse, historic place and museum in Ohio, US
• Great Western Sugar Company, a sugar company headquartered in Denver, Colorado

Ships

• SS Great Western, the first purpose-built trans-Atlantic steamship, 1838
• PS Great Western (1864), owned for a time by the Great Western Railway, later named PS Lovedale
• TSS Great Western (1901), built for GWR, renamed 'GWR No. 20' in 1933
• TSS Great Western (1933), built for the GWR to replace a previous ship of the same name
• USS Great Western, ammunition ship of Union Navy during US Civil War

Other

• Sarah A. Bowman (c. 1813-1866), American innkeeper, restaurateur, and madam
• The Great Western, an album by James Dean Bradfield
• Great Western Building, colonial-era residence, court and hotel in Mumbai, India
• Great Western Cattle Trail, cattle driving trail, US
• The Great Western Chorus of Bristol, a men's a cappella chorus singing primarily in the Barbershop style
• Great Western Loop, long-distance hiking trail in the western US
• Great Western Trail, multiple-use route between Canada and Mexico
• Great Western Trail (board game), based on the Great Western Cattle Trail
• Great Western Turnpike, former series of toll routes in New York state, US
• Great Western Valkyrie, an album by Rival Sons