Gregoria Apaza (June 23, 1751– September 5, 1782) was an indigenous leader in Bolivia.[1] In 1781, she participated with her brother Julian Apaza (Tupac Katari) and sister-in-law Bartolina Sisa in a major indigenous revolt against Spanish colonial rule in Bolivia. These Aymara leaders laid siege to the cities of La Paz and Sorata before being defeated and executed.[2]