Gustavo Gandarillas (born July 19, 1971) is a retired Major League Baseball pitcher. He played during one season at the major league level for the Milwaukee Brewers. He was drafted by the Minnesota Twins in the third round of the 1992 amateur entry draft. Gandarillas played his first professional season with their Rookie League Elizabethton Twins in 1992, and split his last with the Brewers' Triple-A Indianapolis Indians and Double-A Huntsville Stars in 2002.

He played college baseball at the University of Miami.