Hales is a surname. Notable people with the surname include

• Alejandro Hales (1923–2001), Chilean politician
• Alex Hales (born 1989), English cricketer
• Alfred W. Hales (born 1938), American mathematician
• Charles Nicholas Hales (1935–2005), English physician
• Derek Hales (born 1951), English footballer
• Everett Hales (1876–1947), New Zealand cricketer
• E. E. Y. Hales (1908–1986), English historian
• James Hales (c. 1500–1554), English judge, son of above
• John Hales (disambiguation), any of various people of this name
• Laura Harris Hales (1967–2022), American historian and writer
• Robert Hales (disambiguation) any of various people of this name
• R. Stanton Hales (born 1942), American mathematician and educator
• Samuel Hales (1615–1693), founding settler of Hartford and Norwalk, Connecticut
• Stephen Hales (1677–1761), English physiologist, chemist and inventor
• Thomas Hales (disambiguation), any of various people of this name
• Hales, a Triballi king

Hayls

• John Hayls