Hermann Paul August Otto Henking (16 June 1858 – 28 April 1942)[1] was a German cytologist who discovered the X chromosome in 1890 or 1891. The work was the result of a study in Leipzig of the testicles of the firebug (Pyrrhocoris apterus), during which Henking noticed that one chromosome did not take part in meiosis. He named this the X element because its strange behaviour made him unsure whether it was genuinely a chromosome.[2] It was later named the X chromosome after American cytologist Clarence Erwin McClung established that it was not only a genuine chromosome but a sex-determining one, though McClung incorrectly guessed that it was the male-determining sex chromosome.[3]

References

  1. ^ James Wynbrandt, Mark D. Ludman, The Encyclopedia of Genetic Disorders and Birth Defects, page 395, Infobase Publishing, 2009 ISBN 1438120958.
  2. ^ James Schwartz, In Pursuit of the Gene: From Darwin to DNA, pages 155–158, Harvard University Press, 2009 ISBN 0674034910
  3. ^ David Bainbridge, The X in Sex: How the X Chromosome Controls Our Lives, pages 3–5, Harvard University Press, 2003 ISBN 0674016211.


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