Histoid leprosy
SpecialtyDermatology

Histoid leprosy is a skin condition, a rare form of multibacillary leprosy.[1]: 346  It can occur in those with relapsing leprosy after undergoing antibiotic therapy with dapsone, or less frequently in the first infection (termed de novo).[2]

Leprosy can appear in two forms, tuberculoid leprosy and lepromatous leprosy, and histoid leprosy is a variant of lepromatous leprosy. It appears as "cutaneous and/or subcutaneous nodules and papules, which are painless, succulent, discrete, smooth, globular, skin-colored to yellowish-brown, with apparently normal skin surrounding it."[3] In India, histoid leprosy is estimated to compose 2.79%-3.6% of all leprosy cases. The male to female ratio in most parts of the world is 2:1. It is treated with antimycobacterial chemotherapy and multibacillary multidrug therapy.[3]

See also

References

  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ Pandey, Pooja; Suresh, Mavinrkainahalli Srinivasa Murthy; Dey, Vivek Kumar (2015). "De Novo Histoid Leprosy". Indian Journal of Dermatology. 60 (5): 525. doi:10.4103/0019-5154.159666. ISSN 1998-3611. PMC 4601467. PMID 26538746.
  3. ^ a b Gupta, Sunil Kumar (2015-06-20). "Histoid leprosy: review of the literature". International Journal of Dermatology. 54 (11): 1283–1288. doi:10.1111/ijd.12799. ISSN 0011-9059.


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